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Growth Hormone Receptor

Known as: Growth Hormone Receptors, Receptors, Somatotropin [Chemical/Ingredient], Somatotropin Receptors 
Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells. Activation of… 
National Institutes of Health

Related topics

Related topics

11 relations
GHR geneGrowth HormoneHuman Placental LactogenIn Blood

Narrower (2)

GHR protein, humanGHR1 protein, zebrafish

Papers overview

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Highly Cited
2000
Highly Cited
2000
Negative regulation of growth hormone receptor/JAK2 signaling by signal regulatory protein alpha.
Signal regulatory proteins (SIRPs) are receptor-like transmembrane proteins, the majority of which contain a cytoplasmic proline… 
Highly Cited
1999
Highly Cited
1999
Insulin Inhibits Growth Hormone Signaling via the Growth Hormone Receptor/JAK2/STAT5B Pathway*
Insulin is important for maintaining the responsiveness of the liver to growth hormone (GH). Insulin deficiency results in a… 
Highly Cited
1996
Highly Cited
1996
Identification of Tyrosine Residues in the Intracellular Domain of the Growth Hormone Receptor Required for Transcriptional Signaling and Stat5 Activation (*)
The binding of growth hormone (GH) to its receptor results in its dimerization followed by activation of Jak2 kinase and tyrosine… 
Review
1996
Review
1996
Prolactin and growth hormone receptors
The cDNAs encoding growth hormone receptor (GHR) and prolactin receptor (PRLR) were cloned few years ago (Leung et al., 1987… 
Highly Cited
1995
Highly Cited
1995
Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription.
The biological effects of growth hormone (GH) are initiated by its binding to the GH receptor (GHR) followed by association and… 
Highly Cited
1995
Highly Cited
1995
Identification of Phenylalanine 346 in the Rat Growth Hormone Receptor as Being Critical for Ligand-mediated Internalization and Down-regulation (*)
The functional significance of growth hormone (GH) receptor (GHR) internalization is unknown; therefore, we have analyzed domains… 
Highly Cited
1993
Highly Cited
1993
Immunohistochemical and nucleic acid analysis of somatotropin receptor populations in the bovine ovary.
Ovaries were analyzed for somatotropin receptor protein and mRNA through use of immunohistochemistry, solution hybridization… 
Highly Cited
1990
Highly Cited
1990
Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells.
The stimulation of insulin biosynthesis in the pancreatic insulinoma cell line RIN5-AH by growth hormone (GH) is initiated by GH… 
Highly Cited
1989
Highly Cited
1989
Biotechnology in Growth Regulation
Highly Cited
1985
Highly Cited
1985
Evidence from the use of monoclonal antibody probes for structural heterogeneity of the growth hormone receptor.
We describe the use of four monoclonal antibodies (MAbs) to the rabbit liver growth hormone (GH) receptor and one raised against… 
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