Skip to search formSkip to main contentSkip to account menu

GHR protein, human

Known as: GH Receptor, serum binding protein, human, Somatotropin Receptor 
Growth hormone receptor (638 aa, ~72 kDa) is encoded by the human GHR gene. This protein is involved in somatotropin-dependent signaling and… 
National Institutes of Health

Related topics

Related topics

21 relations
AKT Signaling PathwayCell Proliferation Regulatory ProcessCytokine Receptor GeneCytokine Signaling Process

Broader (2)

Growth Hormone Receptorsomatotropin-binding protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Growth Hormone Receptor: Structure Function Relationships
Background: The growth hormone receptor (GHR) was the first class 1 cytokine receptor to be cloned, and it has been studied… 
Highly Cited
2008
Highly Cited
2008
The exon 3-deleted/full-length growth hormone receptor polymorphism did not influence growth response to growth hormone therapy over two years in prepubertal short children born at term with adequate…
CONTEXT Consensus is lacking as to whether the exon 3-deleted (d3)/full-length (fl) GH receptor (GHR) polymorphism is associated… 
2007
2007
The presence of the d3-growth hormone receptor polymorphism is negatively associated with fetal growth but positively associated with postnatal growth in healthy subjects.
CONTEXT A common polymorphism in the GH receptor (GHR) gene has been linked to increased growth response in GH-treated patients… 
2006
2006
A 36 residues insertion in the dimerization domain of the growth hormone receptor results in defective trafficking rather than impaired signaling.
Growth hormone insensitivity syndrome (GHIS) has been reported in a family homozygous for a point mutation in the GH receptor… 
Review
2005
Review
2005
Insulin-Like Growth Factor (IGF) Parameters and Tools for Efficacy: The IGF-I Generation Test in Children
Serum levels of growth hormone (GH)-dependent peptides could provide important and valuable measures of GH sensitivity and… 
Review
2000
Review
2000
Pulsatility of growth hormone (GH) signalling in liver cells: role of the JAK-STAT5b pathway in GH action.
Highly Cited
1997
Highly Cited
1997
Inhibition by interleukin-1 beta and tumor necrosis factor-alpha of the insulin-like growth factor I messenger ribonucleic acid response to growth hormone in rat hepatocyte primary culture.
The cytokines are the putative mediators of the catabolic reaction that accompanies infection and trauma. Evidence suggests that… 
1996
1996
Growth hormone‐binding protein related immunoreactivity is regulated by the degree of insulinopenia in diabetes mellitus
OBJECTIVE Derangements in the GH/IGF axis are common in patients with diabetes mellitus. In insulin‐dependent diabetes mellitus… 
Highly Cited
1994
Highly Cited
1994
Identification and cellular localization of growth hormone receptor gene expression in the human ovary.
While in vivo and in vitro studies in rodents, pigs and women suggest that growth hormone (GH) can stimulate ovarian… 
1990
1990
Characterization of glycosylated bovine placental lactogen and the effect of enzymatic deglycosylation on receptor binding and biological activity.
Bovine placental lactogen (bPL) is a glycoprotein hormone that has both somatogenic and lactogenic properties. Purified… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)