Goserelin

Known as: 6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide, Goserelin [Chemical/Ingredient], Luteinizing hormone-releasing factor (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-10-deglycinamide-, 2-(aminocarbonyl)hydrazide 
A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Ovarian failure is a common toxic effect of chemotherapy. Studies of the use of gonadotropin-releasing hormone (GnRH… (More)
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Highly Cited
2009
Highly Cited
2009
The purpose of this randomized study was to examine if goserelin concomitant to CMF-chemotherapy as adjuvant treatment for… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The Austrian Breast and Colorectal Cancer Study Group trial-12 (ABCSG-12) bone substudy assesses zoledronic acid for… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Among patients using GnRH analogues for endometriosis it has been postulated that peripheral and inflammation-induced… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although chemotherapy and ovarian function suppression are both effective adjuvant therapies for patients with early… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Current adjuvant therapies have improved survival for premenopausal patients with breast cancer but may have short-term… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Effective adjuvant treatment modalities in premenopausal breast cancer patients today include chemotherapy, ovariectomy… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To test the hypothesis that androgen ablation before and during radiotherapy for locally advanced carcinoma of the… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Because the optimal timing of the institution of antiandrogen therapy for prostate cancer is controversial, we… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND We conducted a randomized, prospective trial comparing external irradiation with external irradiation plus goserelin… (More)
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