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Glutaminase Family

Known as: L-Glutamine Amidohydrolase, L-Glutamine Amidohydrolase Family, Glutaminase I 
An enzyme family that cleaves amide bonds to generate glutamate from glutamine. There are two human glutaminase genes that are expressed in a tissue… 
National Institutes of Health

Related topics

Related topics

4 relations
GLS geneGlutaminaseHydrolaseHydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Glutamatergic or GABAergic neuron-specific, long-term expression in neocortical neurons from helper virus-free HSV-1 vectors containing the phosphate-activated glutaminase, vesicular glutamate…
Highly Cited
2000
Highly Cited
2000
Dual Role for the Glutamine Phosphoribosylpyrophosphate Amidotransferase Ammonia Channel
Glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase catalyzes the first reaction of de novopurine nucleotide synthesis… 
Highly Cited
1995
Highly Cited
1995
Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA
Highly Cited
1993
Highly Cited
1993
A 1H/15N n.m.r. study of nitrogen metabolism in cultured mammalian cells.
1. Heteronuclear 1H/15N n.m.r. experiments are described in which 15N labelling of cellular metabolites is detected via their… 
Highly Cited
1991
Highly Cited
1991
Evidence indicating that pig renal phosphate-activated glutaminase has a functionally predominant external localization in the inner mitochondrial membrane.
Highly Cited
1982
Highly Cited
1982
The activities in different neural cell types of certain enzymes associated with the metabolic compartmentation glutamate.
Highly Cited
1982
Highly Cited
1982
Properties of phosphate activated glutaminase in astrocytes cultured from mouse brain
Astrocytes in primary cultures contain a relatively high activity, of phosphate activated glutaminase, although it is… 
Highly Cited
1979
Highly Cited
1979
A role for bicarbonate in the regulation of mammalian glutamine metabolism.
1. The concentration of HCO3- (independent of any change of pH) exerts different effects on glutamine metabolism in rat kidney… 
Highly Cited
1978
Highly Cited
1978
Glutamate dehydrogenase activation and ammonia formation by rat kidney mitochondria.
Mitochondria from rat renal cortex were incubated with physiological concentrations of glutamate, or glutamine, or both. Changes… 
Highly Cited
1976
Highly Cited
1976
Phosphate-dependent glutaminase from rat kidney. Cause of increased activity in response to acidosis and identity with glutaminase from other tissues.
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