Glomerular Filtration Barrier

Known as: Barrier, Glomerular Filtration, Barriers, Glomerular Filtration, Glomerular Filtration Barriers 
A specialized barrier in the kidney, consisting of the fenestrated CAPILLARY ENDOTHELIUM; GLOMERULAR BASEMENT MEMBRANE; and glomerular epithelium… (More)
National Institutes of Health

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Papers overview

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Highly Cited
2010
Highly Cited
2010
A high-powered view of the filtration barrier.
Multiphoton excitation fluorescence microscopy is a powerful noninvasive imaging technique for the deep optical sectioning of… (More)
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Review
2010
Review
2010
Molecular make-up of the glomerular filtration barrier.
The glomerular filtration barrier is composed of glomerular endothelial cells, the glomerulus basement membrane and the podocyte… (More)
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Review
2009
Review
2009
Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier
Glomerular endothelial cell (GEnC) fenestrations are analogous to podocyte filtration slits, but their important contribution to… (More)
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Highly Cited
2009
Highly Cited
2009
Nck proteins maintain the adult glomerular filtration barrier.
Within the glomerulus, the scaffolding protein nephrin bridges the actin-rich foot processes that extend from adjacent podocytes… (More)
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Review
2008
Review
2008
What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium?
Microalbuminuria is an important risk factor for cardiovascular disease and progressive renal impairment. This holds true in the… (More)
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Review
2007
Review
2007
Role of the VEGF--a signaling pathway in the glomerulus: evidence for crosstalk between components of the glomerular filtration barrier.
BACKGROUND/AIMS Vascular endothelial growth factor is a major regulator of angiogenesis and vascular permeability [Carmeliet et… (More)
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Highly Cited
2006
Highly Cited
2006
Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier.
Primary defects in either podocytes or the glomerular basement membrane (GBM) cause proteinuria, a fact that complicates defining… (More)
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Highly Cited
2005
Highly Cited
2005
The human glomerular podocyte is a novel target for insulin action.
Microalbuminuria is significant both as the earliest stage of diabetic nephropathy and as an independent cardiovascular risk… (More)
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Highly Cited
2003
Highly Cited
2003
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases.
Kidney disease affects over 20 million people in the United States alone. Although the causes of renal failure are diverse, the… (More)
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Review
1975
Review
1975
Editorial: The primary glomerular filtration barrier--basement membrane or epithelial slits?
In 1961, based on results obtained with the particulate tracer ferritin, Farquhar, Wissig and Palade [15] proposed a functional… (More)
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