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Global brain atrophy

Known as: Generalized brain atrophy, Generalized cerebral atrophy, Diffuse brain atrophy 
Unlocalized atrophy of the brain with decreased total brain matter volume and increased ventricular size. [HPO:sdoelken]
National Institutes of Health

Related topics

Related topics

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Narrower (1)

Alzheimer's Disease
Amish Infantile Epilepsy SyndromeCerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 2Cerebral atrophyCombined Oxidative Phosphorylation Deficiency 1

Papers overview

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Highly Cited
2006
Highly Cited
2006
Cerebral Palsy in a Term Population: Risk Factors and Neuroimaging Findings
OBJECTIVE. The purpose of this work was to study risk factors and neuroimaging characteristics of cerebral palsy in term and near… 
Highly Cited
2002
Highly Cited
2002
Hippocampal, amygdalar, and global brain atrophy in different apolipoprotein E genotypes
The &egr;4 allele of the APOE gene increases the risk for AD, whereas the &egr;2 allele may be protective. The authors assessed… 
Highly Cited
1997
Highly Cited
1997
Premorbid brain size as a determinant of reserve capacity against intellectual decline in Alzheimer's disease.
OBJECTIVE Both the magnitude of brain atrophy and premorbid brain size determine the volume of the brain affected by Alzheimer's… 
Highly Cited
1997
Highly Cited
1997
MR of childhood metachromatic leukodystrophy.
PURPOSE To investigate the MR findings of childhood metachromatic leukodystrophy (MLD). METHODS Nine MR imaging studies in… 
Review
1995
Review
1995
Ependymal Reactions to Injury. A Review
The ependyma reacts to injury with a few stereotypical responses and does not regenerate at any age. Non-neoplastic ependymal… 
Highly Cited
1994
Highly Cited
1994
Pallido‐pyramidal degeneration, supranuclear upgaze paresis and dementia: Kufor‐Rakeb syndrome
An unusual neurological syndrome in an Arab family with five affected siblings, is reported. Autosomal recessive inheritance is… 
Highly Cited
1990
Highly Cited
1990
Cocaine‐induced seizures
We retrospectively studied 474 patients seen at Hennepin County Medical Center because of medical complications related to acute… 
Highly Cited
1989
Highly Cited
1989
Obsessive-compulsive and other behavioural changes with bilateral basal ganglia lesions. A neuropsychological, magnetic resonance imaging and positron tomography study.
Eight patients are reported who shared the combination of bilateral basal ganglia lesions and a frontal lobe-like syndrome. The… 
Review
1988
Review
1988
Imaging of the aging brain. Part II. Pathologic conditions.
The most common pathologic disorders in the elderly result in dementia, movement disorders, and/or focal neurologic deficit… 
Highly Cited
1987
Highly Cited
1987
Magnetic resonance imaging correlates of dementia in multiple sclerosis.
Thirty-two patients with clinically definite multiple sclerosis were evaluated with neuropsychological procedures and magnetic… 
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