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Gestrinone

Known as: 13-Ethyl-17-Hydroxy-18,19-Dinor-17Alpha-Pregna-4,9,11-Trien-20-Yn-3-One, Pregna-4,9,11-Trien-20-Yn-3-One, 13-Ethyl-17-Hydroxy-18,19-Dinor-, (17Alpha)-, 18,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)- 
A non-estrogenic contraceptive which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can… Expand
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Contraceptives, OralProgestins

Narrower (4)

EM5744NemestranR-2323tetrahydrogestrinone
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Endometriosis: current therapies and new pharmacological developments.
Endometriosis is a chronic inflammatory condition that is responsive to management with steroids. The establishment of a steady… Expand
Review
2008
Review
2008
Medical management of fibroids.
The ideal medical therapy for fibroids is, arguably, a tablet that is taken by mouth, once a day or, even better, once a week… Expand
  • table 1
Highly Cited
2005
Highly Cited
2005
Screening for unknown synthetic steroids in human urine by liquid chromatography-tandem mass spectrometry.
Chemically modified steroids (designer steroids), including tetrahydrogestrinone and norbolethone, pose a threat to the integrity… Expand
Highly Cited
2004
Highly Cited
2004
Tetrahydrogestrinone: discovery, synthesis, and detection in urine.
Tetrahydrogestrinone (18a-homo-pregna-4,9,11-trien-17beta-ol-3-one or THG) was identified in the residue of a spent syringe that… Expand
Review
1994
Review
1994
Treatment of deeply infiltrating endometriosis.
Deep endometriosis has been defined as endometriosis infiltrating deeper than 5 mm under the peritoneum. A model for the… Expand
Highly Cited
1989
Highly Cited
1989
Gestrinone versus danazol in the treatment of endometriosis.
Thirty-nine infertile patients with laparoscopic diagnosis of endometriosis were allocated randomly to treatment with gestrinone… Expand
1989
1989
Long‐term treatment of leiomyomas with gestRinone
A prospective randomized study was conducted in 100 women with leiomyomas in order to evaluate the effect of gestrinone, a… Expand
Highly Cited
1988
Highly Cited
1988
The inhibitory effects of danazol, danazol metabolites, gestrinone, and testosterone on the growth of human endometrial cells in vitro.
Danazol and gestrinone are effective drugs in the treatment of endometriosis. Their mechanism of action remains uncertain, but… Expand
Highly Cited
1987
Highly Cited
1987
Impact of gestrinone on the course of asymptomatic endometriosis.
A new drug, gestrinone, was subjected to the first double blind, randomised placebo controlled trial of any treatment of… Expand
1982
1982
Treatment of endometriosis with gestrinone (R-2323), a synthetic antiestrogen, antiprogesterone.
  • E. Coutinho
  • American journal of obstetrics and gynecology
  • 1982
    • Corpus ID: 44517846
Twenty patients with endometriosis diagnosed by laparoscopy were treated with the antiestrogen, antiprogesterone gestrinone (R… Expand
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