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National Institutes of Health
analogs & derivatives
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Structural Characterization of the Human Androgen Receptor Ligand-binding Domain Complexed with EM5744, a Rationally Designed Steroidal Ligand Bearing a Bulky Chain Directed toward Helix 12*
Journal of Biological Chemistry
Corpus ID: 25853080
Antiandrogens are commonly used to treat androgen-dependent disorders. The currently used drugs unfortunately possess very weak…
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