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Germline DNA

The DNA in germ cells (egg and sperm cells that join to form an embryo). Germline DNA is the source of DNA for all other cells in the body.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Count me in: A patient-driven research initiative to accelerate cancer research.
e13501Background: A challenge in cancer research is the availability of tumor samples linked to clinical information. To address… 
2017
2017
Flow cytometry sorting of nuclei enables the first global characterization of Paramecium germline DNA and transposable elements
DNA elimination is developmentally programmed in a wide variety of eukaryotes, including unicellular ciliates, and leads to the… 
2017
2017
The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation
Base excision repair (BER) is a key genome maintenance pathway. The NEIL1 DNA glycosylase recognizes oxidized bases, and likely… 
2017
2017
Correlation between germline mutations in MMR genes and microsatellite instability in ovarian cancer specimens
A high proportion of ovarian cancers from women who carry germline mutations in mismatch repair (MMR) genes demonstrate… 
2016
2016
Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples
The development of breast and ovarian cancer is strongly connected to the inactivation of the BRCA1 and BRCA2 genes by different… 
2015
2015
High-quality genotyping data from formalin-fixed, paraffin-embedded tissue on the drug metabolizing enzymes and transporters plus array.
2008
2008
Malignant melanoma in patients with hereditary nonpolyposis colorectal cancer
Background  Malignant melanoma (MM) is the most aggressive skin cancer. Most MMs are sporadic, and in this setting an association… 
2004
2004
Highly repetitive DNA families restricted to germ cells in a Japanese hagfish (Eptatretus burgeri): a hierarchical and mosaic structure in eliminated chromosomes
It is known that in eight hagfishes chromosome elimination occurs during early embryogenesis. The eliminated chromosomes are… 
1990
1990
T-cell receptor beta-chain DNA polymorphism frequencies in healthy HLA-DR homozygotes.
In view of numerous recent reports of T-cell receptor (TCR) beta-chain/disease associations with HLA-associated diseases, we… 
1981
1981
Sequence heterogeneity, multiplicity, and genomic organization of alpha- and beta-tubulin genes in sea urchins
We analyzed the multiplicity, heterogeneity, and organization of the genes encoding the alpha and beta tubulins in the sea urchin… 
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