Genome-Wide Association Study
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Both polygenicity (many small genetic effects) and confounding biases, such as cryptic relatedness and population stratification… Expand For most human complex diseases and traits, SNPs identified by genome-wide association studies (GWAS) explain only a small… Expand Summary: Genome-wide association studies (GWAS) have revealed hundreds of loci associated with common human genetic diseases and… Expand We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals… Expand Although genome-wide association studies (GWASs) have identified numerous loci associated with complex traits, imprecise modeling… Expand Uncovering the genetic basis of agronomic traits in crop landraces that have adapted to various agro-climatic conditions is… Expand MOTIVATION
Genome-wide association studies (GWASs) have been widely used to map loci contributing to variation in complex traits… Expand We performed a genome-wide association study (GWAS) in 1,713 individuals of European ancestry with Parkinson's disease (PD) and 3… Expand Whole-genome association studies (WGAS) bring new computational, as well as analytic, challenges to researchers. Many existing… Expand We conducted a genome-wide association study (GWAS) of breast cancer by genotyping 528,173 SNPs in 1,145 postmenopausal women of… Expand