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Genetically Engineered Mouse
Known as:
GEM
A mouse that has been genetically modified by introducing new genetic characteristics to it. It often involves the isolation, manipulation and…
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National Institutes of Health
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Papers overview
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2019
2019
Abstract 3681: RAD51AP1 is a novel therapeutic target for cancer prevention and treatment
Allison E. Bridges
,
Pragya Rajpurohit
,
Parth Patel
,
Nagendra Singh
,
P. Prasad
,
M. Thangaraju
Tumor Biology
2019
Corpus ID: 219269248
Although much progress has been made in recent years in its treatment and prevention, cancer is still the second leading cause of…
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2018
2018
TITLE: Functional Characterization of Novel Melanoma Oncogenes and Tumor Suppressors Utilizing a CRISPR/Cas9 Mouse Model AUTHORS/INSTITUTIONS:
S. Elliott
,
R. Alkallas
,
D. Moldoveanu
,
L. Ramsay
2018
Corpus ID: 166226192
BODY: Body: Genetically Engineered Mouse (GEM) models have been indispensable tools to validate the function of melanoma…
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Review
2018
Review
2018
ROLE OF BMI1 IN PROMOTING BREAST CANCER TUMORIGENESIS THROUGH ATTENUATING THE DNA DAMAGE RESPONSE PATHWAY
C. Ronald MacKenzie
2018
Corpus ID: 81733310
...................................................................................................................... iv…
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2015
2015
A “Mouse Hospital” for Preclinical Testing of Diagnostic and Treatment Modalities in Pancreatic Ductal Adenocarcinoma (PDA)
B. Stanger
2015
Corpus ID: 6622781
Drug development for cancer is a time consuming and costly endeavor. One of the major challenges is choosing which compounds to…
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2013
2013
The role of pathology in the development and evaluation of murine xenograft models of human cancer
Scuola di Dottorato
2013
Corpus ID: 73580357
2012
2012
Award Number: W81XWH-08-1-0453 TITLE: Development of Mouse Models of Ovarian Cancer for Studying Tumor Biology and Testing Novel Molecularly Targeted Therapeutic Strategies. PRINCIPAL INVESTIGATOR:
Cho
,
A. Rehemtulla
2012
Corpus ID: 51828192
Purpose: Genetically engineered mouse (GEM) models of ovarian cancer that closely recapitulate their human tumor counterparts may…
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2012
2012
Abstract 4434: Development of pancreatic ductal adenocarcinoma (PDAC) by the expression of temperature-sensitive SV40 large T antigen (tsTAg) and K-ras G12D on pancreatic epithelial linage cells
Takashi Yamaguchi
,
Sanae Ikehara
,
M. Hashimoto
,
A. Sato
,
H. Nakanishi
,
Y. Ikehara
2012
Corpus ID: 56929056
Based on studies using genetically engineered mouse (GEM) models producing pancreatic ductal adenocarcinoma (PDAC), pancreatic…
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2011
2011
Investigation of T cell-mediated immune surveillance against tumor-specific antigens in genetically engineered mouse models of cancer
Parfums Du
,
Michael J Porter
2011
Corpus ID: 83321242
The association of tumor cells and lymphocytes has led to the hypothesis that our immune system actively inhibits the formation…
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2004
2004
Type XIII collagen : organization of the mouse gene, generation of three genetically engineered mouse lines by homologous recombination, and biochemical studies on the molecular properties of the…
Anne Latvanlehto
2004
Corpus ID: 85661048
2002
2002
The EU Kyoto target and the choice of policy instruments, the contribution of a general equilibrium analysis with GEM-E3 compared to a partial equilibrium analysis
Stef Proost
,
D. van Regemorter
2002
Corpus ID: 157385924