FAQ

Genetically Engineered Mouse

Known as: GEM 
A mouse that has been genetically modified by introducing new genetic characteristics to it. It often involves the isolation, manipulation and… (More)

Topic mentions per year

Topic mentions per year

2002-2017
024620022017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Stem cells in genetically-engineered mouse models of prostate cancer.
The cancer stem cell model proposes that tumors have a hierarchical organization in which tumorigenic cells give rise to non… (More)
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2015
2015
Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
Multiple mechanisms have been described that confer BRAF inhibitor resistance to melanomas, yet the basis of this resistance… (More)
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2013
2013
Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer
Capecitabine (CAP) is a 5-FU pro-drug approved for the treatment of several cancers and it is used in combination with… (More)
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2011
2011
Antitumor activity of the investigational proteasome inhibitor MLN9708 in mouse models of B-cell and plasma cell malignancies.
PURPOSE The clinical success of the first-in-class proteasome inhibitor bortezomib (VELCADE) has validated the proteasome as a… (More)
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2011
2011
Gold Nanorod Photothermal Therapy in a Genetically Engineered Mouse Model of Soft Tissue Sarcoma
Plasmonic nanomaterials are poised to impact the clinical management of cancer through their ability to convert externally… (More)
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Review
2009
Review
2009
Influence of genetic background on genetically engineered mouse phenotypes.
The history of mouse genetics, which involves the study of strain-dependent phenotype variability, makes it clear that the… (More)
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2009
2009
Corrigendum: Refining timed pregnancies in two strains of genetically engineered mice
In order to efficiently generate genetically engineered mouse (GEM) fetuses or neonates of a specified age range, researchers… (More)
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2008
2008
Editorial: best pathology practices in research using genetically engineered mice.
The recent advent of high-throughput transgenic and gene targeting technologies has accelerated the generation of new genetically… (More)
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2008
2008
A scintillating gas detector for 2D dose measurements in clinical carbon beams.
A two-dimensional position sensitive dosimetry system based on a scintillating gas detector has been developed for pre-treatment… (More)
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2005
2005
Intrasplenic Transplantation of Encapsulated Genetically Engineered Mouse Insulinoma Cells Reverses Streptozotocin-Induced Diabetes in Rats.
Pancreatic islet transplantation is limited by shortage of donor organs. Although β-cell lines could be used, their secretion of… (More)
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