Genes, Essential

Known as: Essential Gene, Essential Genes, Gene, Essential 
Those genes found in an organism which are necessary for its viability and normal function.

Topic mentions per year

Topic mentions per year

1999-2018
0102019992018

Papers overview

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2016
2016
Essential gene functions underpin the core reactions required for cell viability, but their contributions and relationships are… (More)
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2015
2015
Defining the essential genome of bacterial pathogens is central to developing an understanding of the biological processes… (More)
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Highly Cited
2013
Highly Cited
2013
Understanding the core set of genes that are necessary for basic developmental functions is one of the central goals in biology… (More)
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2012
2012
BACKGROUND Essential genes are absolutely required for the survival of an organism. The identification of essential genes… (More)
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Highly Cited
2011
Highly Cited
2011
High-content screening for gene profiling has generally been limited to single cells. Here, we explore an alternative approach… (More)
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2009
2009
Wolbachia (wBm) is an obligate endosymbiotic bacterium of Brugia malayi, a parasitic filarial nematode of humans and one of the… (More)
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2007
2007
We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen… (More)
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2007
2007
In most species, and particularly in vertebrates, the percentage of genes absolutely required for survival, the essential genes… (More)
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Highly Cited
2004
Highly Cited
2004
Essential genes are genes that are indispensable to support cellular life. These genes constitute a minimal gene set required for… (More)
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Highly Cited
2004
Highly Cited
2004
Little is known about the genes that regulate telomere length diversity between mammalian species. A candidate gene locus was… (More)
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