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Genes, Essential

Known as: Essential Gene, Essential Genes, Gene, Essential 
Those genes found in an organism which are necessary for its viability and normal function.
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Somatic gene mutations can alter the vulnerability of cancer cells to T-cell-based immunotherapies. Here we perturbed genes in… Expand
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Highly Cited
2015
Highly Cited
2015
Zeroing in on essential human genes More powerful genetic techniques are helping to define the list of genes required for the… Expand
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Highly Cited
2009
Highly Cited
2009
Essential genes are those indispensable for the survival of an organism, and their functions are therefore considered a… Expand
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Highly Cited
2008
Highly Cited
2008
More complete knowledge of the molecular mechanisms underlying cancer will improve prevention, diagnosis and treatment. Efforts… Expand
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Highly Cited
2003
Highly Cited
2003
To estimate the minimal gene set required to sustain bacterial life in nutritious conditions, we carried out a systematic… Expand
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Highly Cited
2003
Highly Cited
2003
Defining the gene products that play an essential role in an organism's functional repertoire is vital to understanding the… Expand
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Highly Cited
2003
Highly Cited
2003
Candida albicans is the primary fungal pathogen of humans. Despite the need for novel drugs to combat fungal infections [Sobel, J… Expand
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Highly Cited
2001
Highly Cited
2001
We report the first RNAi-induced phenotypes in mammalian cultured cells using RNA interference mediated by duplexes of 21-nt RNAs… Expand
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Highly Cited
2001
Highly Cited
2001
An increasing number of microbial genomes have been completely sequenced, and the identified genes are categorized based on their… Expand
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Highly Cited
1995
Highly Cited
1995
We have constructed a series of plasmid vectors (pBAD vectors) containing the PBAD promoter of the araBAD (arabinose) operon and… Expand
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