Gemfibrozil

Known as: Gemfibrozilo, Gemfibrosil, Gemfibrozilum 
A fibric acid derivative with hypolipidemic effects. Gemfibrozil interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute carriers are more and more recognized… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Changes in conventional lipid risk factors with gemfibrozil treatment only partially explain the reductions in… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Coadministration of statins and gemfibrozil is associated with an increased risk for myopathy, which may be due in… (More)
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Highly Cited
2004
Highly Cited
2004
A serious pharmacokinetic interaction between cerivastatin (CER) and gemfibrozil (GEM) has been reported. In the present study… (More)
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Highly Cited
2003
Highly Cited
2003
Aims/hypothesis. Our aim was to investigate possible interactions of gemfibrozil, itraconazole, and their combination with… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Concomitant use of gemfibrozil with statins, particularly with cerivastatin, increases the risk of rhabdomyolysis, but… (More)
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Highly Cited
2002
Highly Cited
2002
A series of studies were conducted to explore the mechanism of the pharmacokinetic interaction between simvastatin (SV) and… (More)
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Highly Cited
2001
Highly Cited
2001
CONTEXT A low plasma level of high-density lipoprotein cholesterol (HDL-C) is a major risk factor for coronary heart disease (CHD… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND A low level of HDL cholesterol has been identified as a risk factor for stroke in observational studies. METHODS AND… (More)
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Highly Cited
2000
Highly Cited
2000
A BSTRACT Background Although it is generally accepted that lowering elevated serum levels of low-density lipoprotein (LDL… (More)
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