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Gemfibrozil

Known as: Gemfibrozilo, Gemfibrosil, Gemfibrozilum 
A fibric acid derivative with hypolipidemic effects. Gemfibrozil interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in… 
National Institutes of Health

Related topics

Related topics

42 relations

Broader (4)

Anticholesteremic AgentsCytochrome P-450 CYP2C8 InhibitorsHypolipidemic Agentscarboxylate

Narrower (12)

AusgemCI 924CI-719Gemfi 1A Pharma
Biliary cirrhosisCerivastatin sodiumCoronary Artery DiseaseDecreased Lipolysis [PE]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Applicability of sucrose laurate as surfactant in solid dispersions prepared by melt technology.
Highly Cited
2007
Highly Cited
2007
Pharmacokinetic comparisons of tail-bleeding with cannula- or retro-orbital bleeding techniques in rats using six marketed drugs.
Highly Cited
2001
Highly Cited
2001
Effect of statin versus fibrate on postprandial endothelial dysfunction: role of remnant-like particles.
Highly Cited
2001
Highly Cited
2001
Gemfibrozil increases paraoxonase activity in type 2 diabetic patients. A new hypothesis of the beneficial action of fibrates?
OBJECTIVE The constellation of elevated triglycerides and decreased high-density lipoprotein is recognised as a risk factor for… 
Review
1999
Review
1999
The regulation of acetyl-CoA carboxylase--a potential target for the action of hypolipidemic agents.
Highly Cited
1994
Highly Cited
1994
Evaluation of a rodent peroxisome proliferator in two species of freshwater fish: rainbow trout (Onchorynchus mykiss) and Japanese medaka (Oryzias latipes)
Highly Cited
1993
Highly Cited
1993
Rationale and design of the Department of Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial (HIT) for secondary prevention of coronary artery disease in men with low high…
Highly Cited
1992
Highly Cited
1992
Direct Effects of Gemfibrozil on the Fibrinolytic System: Diminution of Synthesis of Plasminogen Activator Inhibitor Type 1
BackgroundPlatelet-associated epidermal growth factor (EGF) and transforming growth factor-β (TGF-β) can augment synthesis of… 
Highly Cited
1992
Highly Cited
1992
Gemfibrozil Reduces Plasma Prothrombin Fragment F1+2 Concentration, a Marker of Coagulability, in Patients with Coronary Heart Disease
Summary The effects of gemfibrozil on several indices of haemostatic activity were explored in male patients with coronary heart… 
Review
1988
Review
1988
Management of lipids in primary and secondary prevention of cardiovascular diseases.
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