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Gefarnate
Known as:
Gefarnate [Chemical/Ingredient]
, 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, 3,7-dimethyl-2,6-octadienyl ester, (E,E,E)-
, Farnesylacetate, Geranyl
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A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function of mucosal tissue.
National Institutes of Health
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Related topics
Related topics
13 relations
Broader (1)
Anti-Ulcer Agent
Narrower (5)
Gefarnil
Gepharnate
Ulco
gefarnax
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In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Multinational, double-blind, randomised, placebo-controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER* study
K. Sugano
,
Myung-Gyu Choi
,
+11 authors
M. Date
Gut
2013
Corpus ID: 30234059
Objectives To evaluate if esomeprazole prevents recurrent peptic ulcer in adult patients with a history of peptic ulcer receiving…
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Highly Cited
2004
Highly Cited
2004
Character of ocular surface mucins and their alteration in dry eye disease.
I. Gipson
,
Y. Hori
,
P. Argüeso
The ocular surface
2004
Corpus ID: 32313238
2002
2002
Gefarnate stimulates goblet cell repopulation following an experimental wound to the tarsal conjunctiva in the dry eye rabbit.
H. Toshida
,
K. Nakata
,
T. Hamano
,
Masatsugu Nakamura
,
D. Nguyen
,
R. Beuerman
Advances in Experimental Medicine and Biology
2002
Corpus ID: 32160825
Geranyl farnesylacetate (gefarnate) has been used to stimulate mucin production from goblet cells of patients who have gastritis…
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1998
1998
Gefarnate increases PAS positive cell density in rabbit conjunctiva
Masatsugu Nakamura
,
K. Endo
,
K. Nakata
,
T. Hamano
British Journal of Ophthalmology
1998
Corpus ID: 7554782
AIMS The effects of three drugs for the treatment of gastritis and gastric ulcer—gefarnate, ecabet sodium, and troxipide—on…
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1997
1997
Gefarnate stimulates secretion of mucin-like glycoproteins by corneal epithelium in vitro and protects corneal epithelium from desiccation in vivo.
M. Nakamura
,
K. Endo
,
K. Nakata
,
T. Hamano
Experimental Eye Research
1997
Corpus ID: 26126884
The effect of drugs for gastritis and gastric ulcer (ecabet sodium, gefarnate, teprenone, and troxipide) on the secretion of…
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Highly Cited
1989
Highly Cited
1989
Evaluation of the gastric antiulcerogenic effects of Solanum nigrum, Brassica oleracea and Ocimum basilicum in rats.
Muhammad Shoaib Akhtar
,
Muhammad Munir
Journal of Ethnopharmacology
1989
Corpus ID: 21471824
Highly Cited
1985
Highly Cited
1985
[Effects of gefarnate on acute gastric lesions in rats].
N. Hara
,
S. Okabe
Nihon yakurigaku zasshi. Folia pharmacologica…
1985
Corpus ID: 38011125
The effects of gefarnate on several acute gastric lesions were studied in rats. Gefarnate, given at either 100 approximately 1000…
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Review
1985
Review
1985
Pirenzepine
A. Carmine
,
Brogden Rn
Drugs
1985
Corpus ID: 195691994
SummarySynopsis: Pirenzepine1 is a ‘selective’ tantimuscarinic agent which, unlike classic anticholinergic agents, inhibits…
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Highly Cited
1981
Highly Cited
1981
Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats.
M. Murakami
,
K. Oketani
,
H. Fujisaki
,
T. Wakabayashi
,
T. Ohgo
Arzneimittel-Forschung
1981
Corpus ID: 44344089
Antinuclear effects of geranylgeranylacetone (GGA), new acyclic polyisoprenoid, on several types of experimental gastric and…
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1973
1973
Treatment of Chronic Gastric Ulcer with Carbenoxolone and Gefarnate: A Comparative Trial
M. Langman
,
D. Knapp
,
E. J. Wakley
British medical journal
1973
Corpus ID: 25607016
In 68 patients with chronic gastric ulcer treated in an outpatient clinical trial with either carbenoxolone or gefarnate ulcer…
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