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Gefarnate

Known as: Gefarnate [Chemical/Ingredient], 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, 3,7-dimethyl-2,6-octadienyl ester, (E,E,E)-, Farnesylacetate, Geranyl 
A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function of mucosal tissue.
National Institutes of Health

Related topics

Related topics

13 relations

Broader (1)

Anti-Ulcer Agent

Narrower (5)

GefarnilGepharnateUlcogefarnax
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Gefarnate stimulates goblet cell repopulation following an experimental wound to the tarsal conjunctiva in the dry eye rabbit.
Geranyl farnesylacetate (gefarnate) has been used to stimulate mucin production from goblet cells of patients who have gastritis… 
2002
2002
Effect of Gefarnate on the Ocular Surface in Squirrel Monkeys
Purpose. To investigate the ability of gefarnate (geranyl farnesylacetate) to stimulate goblet cell function in the primate eye… 
1998
1998
Gefarnate increases PAS positive cell density in rabbit conjunctiva
AIMS The effects of three drugs for the treatment of gastritis and gastric ulcer—gefarnate, ecabet sodium, and troxipide—on… 
1997
1997
Gefarnate stimulates secretion of mucin-like glycoproteins by corneal epithelium in vitro and protects corneal epithelium from desiccation in vivo.
The effect of drugs for gastritis and gastric ulcer (ecabet sodium, gefarnate, teprenone, and troxipide) on the secretion of… 
1991
1991
A new method for evaluating gastric ulcer healing by endoscopic ultrasonography.
We observed the quantitative estimation of the transmural changes associated with gastric ulcer healing by using endoscopic… 
1983
1983
Difference in mode of action of cimetidine and gefarnate on endogenous prostacyclin, prostaglandin E2 and thromboxane in rat gastric mucosa.
The effects of cimetidine and gefarnate on endogenous prostacyclin, prostaglandin E2 and thromboxane were studied in vivo in rat… 
1983
1983
Effect of gefarnate on endogenous prostacyclin, prostaglandin E2 and thromboxane in water-immersed rats.
The level of endogenous prostacyclin (PGI2), prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) in rat gastric mucosa was… 
1982
1982
Effects of the antiulcer drug geranylgeranylacetone on aspirin-induced gastric ulcers in rats.
Antiulcer effects of geranylgeranylacetone (GGA) on aspirin-induced gastric ulcers in rats were studied, comparing them with… 
1974
1974
The mechanism of action of gefarnate in the light of the latest data on digestive physiopathology.
SummaryA study to investigate the mechanism of action of gefarnate (treatment: 600 mg. daily by mouth for 30 days) was carried… 
1973
1973
Treatment of Chronic Gastric Ulcer with Carbenoxolone and Gefarnate: A Comparative Trial
In 68 patients with chronic gastric ulcer treated in an outpatient clinical trial with either carbenoxolone or gefarnate ulcer… 
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