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Gefarnate
Known as:
Gefarnate [Chemical/Ingredient]
, 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, 3,7-dimethyl-2,6-octadienyl ester, (E,E,E)-
, Farnesylacetate, Geranyl
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A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function of mucosal tissue.
National Institutes of Health
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Related topics
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13 relations
Broader (1)
Anti-Ulcer Agent
Narrower (5)
Gefarnil
Gepharnate
Ulco
gefarnax
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In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1987
1987
A new screening method for anti-ulcer agents: psychological stress produced by intraspecies emotional communication.
Y. Ichimaru
,
Y. Gomita
Pharmacology
1987
Corpus ID: 3318462
Psychological stress produced by intraspecies emotional communication in a communication box was studied to see whether it could…
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1985
1985
A comparison of alprazolam, gefarnate and their combination in treatment of peptic ulcer patients--an application of life table analysis.
N. Ogawa
,
M. Namiki
,
T. Kusunoki
,
S. Fujii
International journal of clinical pharmacology…
1985
Corpus ID: 32626743
One hundred and thirty-nine patients with endoscopically confirmed peptic ulcers (gastric and duodenal) entered a double blind…
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1983
1983
Effect of gefarnate on endogenous prostacyclin, prostaglandin E2 and thromboxane in water-immersed rats.
K. Kobayashi
,
T. Arakawa
,
+4 authors
T. Ono
Tohoku journal of experimental medicine
1983
Corpus ID: 38938803
The level of endogenous prostacyclin (PGI2), prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) in rat gastric mucosa was…
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1979
1979
Double blind comparison between cimetidine and gefarnate in cases of duodenal ulcer.
M. Cambielli
,
A. Evangelista
,
M. Guslandi
,
L. Bierti
,
C. Benvenuti
,
A. Tittobello
Acta hepato-gastroenterologica
1979
Corpus ID: 20375441
Thirty outpatients suffering from duodenal ulcer of recent onset were given cimetidine 1 g/day or gefarnate 250 mg/day for 6…
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1979
1979
Studies on the mechanism of action of cetraxate [4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride], a new anti-ulcer agent.
Y. Suzuki
,
M. Itô
,
Y. Sudo
Japanese Journal of Pharmacology
1979
Corpus ID: 35738981
To elucidate mechanisms involved in the anti-ulcer action of cetraxate, the effects of this agent on the ulcer index (UI…
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1976
1976
Relation of Recurrence of Gastric Ulcers to Fundal Gastritis and Effect of Gefarnate in Preventing Recurrence
M. Tatsuta
,
S. Okuda
1976
Corpus ID: 72655492
Summary The extents of fundal gastritis in 136 out-patients with healed gastric ulcers were examined by the endoscopic Congo red…
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1976
1976
Treatment of chronic gastric ulcer with gefarnate: a long-term controlled therapeutic trial.
S. Truelove
,
M. Rocca
Current Medical Research and Opinion
1976
Corpus ID: 28851757
A long-term controlled therapeutic trial of gefarnate (600 mg daily) in the treatment of chronic gastric ulcer was carried out in…
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1974
1974
Proceedings: A double blind trial of carbenoxolone and geranyl farnesylacetate in gastric ulcer.
Smith Pm
,
Sladen Ge
,
Langman Mj
,
Lennard-Jones Je
1974
Corpus ID: 77095331
1972
1972
Effect of anti-ulcer drugs on gastric mucous hexosamine in rats subjected to several ulcerogenic conditions.
K. Takagi
,
S. Yano
Chemical and pharmaceutical bulletin
1972
Corpus ID: 6973859
Hexosamine content of pyloric tissue of the stomach in rats exposed to fasting, water immersion and restraint stress, and…
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1963
1963
[CLINICAL EVALUATION OF A NEW ANTI-ULCER PRODUCT (GERANYL FARNESYLACETATE)].
R. Bertero
,
C. Saracco
,
G. Bruno
Minerva gastroenterologica
1963
Corpus ID: 27460994
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