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Gastrointestinal Lipase Inhibitor

Any substance that inhibits gastrointestinal lipase, an enzyme that is involved in the absorption of dietary lipids. Inhibition of gastrointestinal… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Antiobesity treatment is recommended for selected patients in whom lifestyle modification is unsuccessful. Two antiobesity drugs… Expand
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Highly Cited
2007
Highly Cited
2007
Orlistat is an oral inhibitor of gastrointestinal lipase used for weight reduction in obese patients. Although most adverse drug… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE The purpose of this study was to assess the effect of orlistat, a gastrointestinal lipase inhibitor, on body weight… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Orlistat is a gastrointestinal lipase inhibitor that reduces dietary fat absorption by approximately 30%, promotes… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To evaluate the long-term efficacy and tolerability within primary care settings of orlistat, a gastrointestinal lipase… Expand
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Highly Cited
1999
Highly Cited
1999
CONTEXT Orlistat, a gastrointestinal lipase inhibitor that reduces dietary fat absorption by approximately 30%, may promote… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Long-term maintenance of weight loss remains a therapeutic challenge in obesity treatment. OBJECTIVE This… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND We undertook a randomised controlled trial to assess the efficacy and tolerance of orlistat, a gastrointestinal lipase… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND We undertook a randomised controlled trial to assess the efficacy and tolerability of orlistat, a gastrointestinal… Expand
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Review
1992
Review
1992
Excessive intake of dietary fat contributes to the development and maintenance of both obesity and hyperlipidemia. Inhibition of… Expand
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