Gastrointestinal Lipase Inhibitor

Any substance that inhibits gastrointestinal lipase, an enzyme that is involved in the absorption of dietary lipids. Inhibition of gastrointestinal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2016
024619922016

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2009
2009
AIMS To assess the efficacy, pharmacodynamics, safety and tolerability of a range of doses of cetilistat, a novel inhibitor of… (More)
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2008
2008
OBJECTIVE The purpose of this study was to examine the possible effects of a gastrointestinal lipase inhibitor "Orlistat (Xenical… (More)
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2007
2007
Orlistat is an oral inhibitor of gastrointestinal lipase used for weight reduction in obese patients. Although most adverse drug… (More)
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2004
2004
BACKGROUND Unabsorbed fat and bile acids may react with calcium in the intestinal lumen, limiting the amount of free calcium… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To evaluate the long-term efficacy and tolerability within primary care settings of orlistat, a gastrointestinal lipase… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Long-term maintenance of weight loss remains a therapeutic challenge in obesity treatment. OBJECTIVE This… (More)
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Highly Cited
1999
Highly Cited
1999
CONTEXT Orlistat, a gastrointestinal lipase inhibitor that reduces dietary fat absorption by approximately 30%, may promote… (More)
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1999
1999
Orlistat, a gastrointestinal lipase inhibitor, decreases fat absorption and thus it reduces caloric intake. The objectives of… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND We undertook a randomised controlled trial to assess the efficacy and tolerability of orlistat, a gastrointestinal… (More)
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1994
1994
The effect of orlistat, a nonabsorbed inhibitor of gastric and pancreatic lipases, was examined in patients with primary… (More)
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