GZMH gene

Human ageing affects the immune system resulting in an overall decline in immunocompetence. Although all immune cells are… Expand

The granzyme/perforin pathway is a major mechanism for cytotoxic lymphocytes to eliminate virus-infected and tumor cells. The… Expand

Human granzyme H (GzmH) is constitutively expressed in human NK cells that have important roles in innate immune responses… Expand

Granzymes are key components of the cytotoxic arm of the immune response, which play critical roles in eliminating host cells… Expand

A novel lysozyme cDNA from the Pacific oyster, Crassostrea gigas, was identified. This second lysozyme from the Pacific oyster… Expand

Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular… Expand

Granzyme H (GzmH) belongs to a family of 5 human serine proteases that are expressed by cytotoxic immune effector cells. Although… Expand

Granzymes (Gzm) are a group of serine proteases which are stored in the granules of cytotoxic lymphocytes. In humans, five… Expand

We analyzed the expression of granzyme H in human blood leukocytes, using a novel monoclonal antibody raised against recombinant… Expand

We previously identified a cluster of hematopoietic serine protease genes on chromosome 14 at band q11.2. This cluster contains… Expand