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GZMH gene
Known as:
CGL2
, CTSGL2
, CTLA1
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National Institutes of Health
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1 relation
GZMB gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes
L. Tserel
,
R. Kolde
,
+8 authors
P. Peterson
Scientific Reports
2015
Corpus ID: 19511761
Human ageing affects the immune system resulting in an overall decline in immunocompetence. Although all immune cells are…
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2013
2013
Identification of SERPINB1 As a Physiological Inhibitor of Human Granzyme H
Li Wang
,
Qian Li
,
+11 authors
Z. Fan
Journal of Immunology
2013
Corpus ID: 43031962
The granzyme/perforin pathway is a major mechanism for cytotoxic lymphocytes to eliminate virus-infected and tumor cells. The…
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2012
2012
Structural Insights into the Substrate Specificity of Human Granzyme H: The Functional Roles of a Novel RKR Motif
Li Wang
,
Kai Zhang
,
+6 authors
Z. Fan
Journal of Immunology
2012
Corpus ID: 27165592
Human granzyme H (GzmH) is constitutively expressed in human NK cells that have important roles in innate immune responses…
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2012
2012
Granzyme H of Cytotoxic Lymphocytes Is Required for Clearance of the Hepatitis B Virus through Cleavage of the Hepatitis B Virus X Protein
Haidong Tang
,
Chong Li
,
Li Wang
,
Honglian Zhang
,
Z. Fan
Journal of Immunology
2012
Corpus ID: 9960409
The granule exocytosis pathway of cytotoxic lymphocytes plays critical roles in eradication of intracellular viruses. However…
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Review
2008
Review
2008
Death by a thousand cuts: granzyme pathways of programmed cell death.
D. Chowdhury
,
J. Lieberman
Annual Review of Immunology
2008
Corpus ID: 207690110
The granzymes are cell death-inducing enzymes, stored in the cytotoxic granules of cytotoxic T lymphocytes and natural killer…
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Highly Cited
2008
Highly Cited
2008
Granzyme H induces apoptosis of target tumor cells characterized by DNA fragmentation and Bid-dependent mitochondrial damage.
Q. Hou
,
T. Zhao
,
+4 authors
Z. Fan
Molecular Immunology
2008
Corpus ID: 22017377
2007
2007
cDNA cloning and in situ hybridization of a novel lysozyme in the Pacific oyster, Crassostrea gigas.
N. Itoh
,
Keisuke G. Takahashi
Comparative Biochemistry and Physiology Part B…
2007
Corpus ID: 37273341
Highly Cited
2007
Highly Cited
2007
Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition
F. Andrade
,
E. Fellows
,
D. Jenne
,
A. Rosen
,
Csh Young
EMBO Journal
2007
Corpus ID: 31635496
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular…
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Highly Cited
2004
Highly Cited
2004
Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes*
K. Sedelies
,
T. Sayers
,
+4 authors
J. Trapani
Journal of Biological Chemistry
2004
Corpus ID: 38577788
We analyzed the expression of granzyme H in human blood leukocytes, using a novel monoclonal antibody raised against recombinant…
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Highly Cited
1991
Highly Cited
1991
Structure and expression of a cluster of human hematopoietic serine protease genes found on chromosome 14q11.2.
J. Heusel
,
R. Hanson
,
G. Silverman
,
T. Ley
Journal of Biological Chemistry
1991
Corpus ID: 22347211
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