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GTS-21

Known as: GTS 21 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The cholinergic antiinflammatory pathway modulates Inflammatory cytokine production through a mechanism dependent on the vagus… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Tumor necrosis factor and high mobility group box 1 are critical cytokine mediators of inflammation. The efferent vagus… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS The nervous system, through the vagus nerve, controls inflammation by decreasing the release of tumor necrosis… Expand
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Highly Cited
2003
Highly Cited
2003
This study was designed to determine the safety, tolerability, pharmacokinetics and effects on cognitive function of GTS-21 in… Expand
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Highly Cited
2002
Highly Cited
2002
1. Pharmacological studies of alpha7 nicotinic acetylcholine receptors are confounded by the fact that rapid desensitization to… Expand
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Review
2000
Review
2000
A large decrease in brain nicotinic receptor levels occurs in Alzheimer's disease, relative to muscarinic and other receptors… Expand
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1998
1998
The neuroprotective effects of GTS-21 [3-(2,4-dimethoxybenzylidene)-anabaseine dihydrochloride] were studied and compared with… Expand
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Highly Cited
1997
Highly Cited
1997
(2.4)-Dimethoxybenzylidene anabaseine dihydrochloride (GTS-21), a compound that interacts with rat neuronal nicotinic… Expand
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Highly Cited
1995
Highly Cited
1995
The ability of two synthetic nicotine receptor ligands, TGS-21 and DMAB, to chronically enhance the cognitive function of aged… Expand
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1994
1994
The septo-hippocampal cholinergic system is of demonstrated involvement in eyeblink classical conditioning (EBCC). To determine… Expand
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