Skip to search formSkip to main content

GTI2040

Known as: GTI 2040, GTI-2040 
A substance being studied in the treatment of cancer. It blocks the production of a protein called ribonucleotide reductase, which helps cells make… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
BACKGROUND Heparin-induced thrombocytopenia (HIT) is a rare complication of heparin therapy resulting from antibody production to… Expand
Is this relevant?
2009
2009
BackgroundGTI-2040 is a 20-mer antisense oligonucleotide targeting the mRNA of ribonucleotide reductase M2. It was combined with… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
2008
2008
BACKGROUND The expression and activity of ribonucleotide reductase (RR) has been associated with resistance to multiple drugs in… Expand
Is this relevant?
2008
2008
PURPOSE Inhibition of ribonucleotide reductase reduces the availability of the endogenous pool of deoxycytidine and may increase… Expand
  • table 1
  • table 3
  • table 2
  • table 4
  • figure 1
Is this relevant?
2006
2006
GTI-2040 is a 20-mer phosphorothioate oligonucleotide, which is complementary to the messenger ribonucleic acid (mRNA) of the R2… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
2006
2006
This study describes the development of a rapid and practical real-time RT-PCR method to quantify ribonucleotide reductase M2… Expand
  • table I
  • figure 1
  • figure 2
Is this relevant?
2005
2005
BACKGROUND This study of GTI-2040, a 20-mer phosphorothioate oligonucleotide complementary to the messenger ribonucleic acid… Expand
  • table 1
  • table 3
  • table 2
  • table 4
  • table 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
GTI-2040 is a 20-mer oligonucleotide that is complementary to a coding region in the mRNA of the R2 small subunit component of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?