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GT 2331

Known as: GT-2331 
 
National Institutes of Health

Papers overview

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2007
2007
GT-2331 [(+)-1] is one of the most potent members of a class of chiral drug substances used to regulate the synthesis and release… Expand
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2006
2006
Histamine H(3) receptor antagonists are potential therapeutic agents for cognitive dysfunction, epilepsy, hypersomnia and obesity… Expand
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2005
2005
Previously reported pharmacological studies using the imidazole-containing histamine H3 receptor ligands GT-2331 (Cipralisant… Expand
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2004
2004
GT-2331 is a potent histamine H(3) antagonist which has entered clinical trials. Efficient multigram syntheses of this compound… Expand
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2002
2002
Histamine H(3) receptor antagonists have been proposed as potentially useful therapeutic agents for the treatment of several… Expand
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2002
2002
The selective H(3) receptor agonist (R)-alpha-methylhistamine [(R)-alpha-MeHA] stimulates drinking in the adult rat. In the… Expand
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2000
2000
The histamine H3 receptor provides a negative feedback mechanism for the release and synthesis of histamine. On non-histaminergic… Expand
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1999
1999
Previously, a novel series of 1H-4-substituted imidazole compounds were described as potent and selective histamine (HA) H3… Expand
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1998
1998
GT-2227 (4-(6-cyclohexylhex-cis-3-enyl)imidazole) and GT-2331 ((1R,2R)-4-(2-(5,5-dimethylhex-1-ynyl)cyclopropyl)imidazole) were… Expand
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