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GSTP1 gene

Known as: GSTP, GSTP1, GLUTATHIONE S-TRANSFERASE, PI 
This gene is involved in phase II metabolism of both endogenous compounds and xenobiotics.
National Institutes of Health

Related topics

Related topics

8 relations
Ethanol MetabolismGSTP1P1 geneGlutathione S-Transferase PMetabolic Detoxication, Drug

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GSTP1 wt Allele

Papers overview

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2012
2012
Ubiquitin–Proteasome System Impairment and MPTP-Induced Oxidative Stress in the Brain of C57BL/6 Wild-type and GSTP Knockout Mice
The ubiquitin–proteasome system (UPS) is the primary proteolytic complex responsible for the elimination of damaged and misfolded… 
Highly Cited
2009
Highly Cited
2009
Markedly enhanced colon tumorigenesis in ApcMin mice lacking glutathione S-transferase Pi
Glutathione transferases are a multigene family of proteins that catalyze the conjugation of toxic electrophiles and carcinogens… 
2007
2007
Histone acetyltransferase MOZ acts as a co-activator of Nrf2-MafK and induces tumour marker gene expression during hepatocarcinogenesis.
HATs (histone acetyltransferases) contribute to the regulation of gene expression, and loss or dysregulation of these activities… 
2007
2007
Polymorphisms of GSTP 1 and GSTT 1 , but not of CYP 2 A 6 , CYP 2 E 1 or GSTM 1 , modify the risk for esophageal cancer in a western population
A.Rossini, D.C.M.Rapozo, S.C.Soares Lima, D.P.Guimarães, M.A.Ferreira, R.Teixeira, C.D.P.Kruel, S.G.S.Barros, N.A.Andreollo, R… 
2006
2006
Methylation Profiling of Urothelial Carcinoma in Bladder Biopsy and Urine
OBJECTIVE To test DNA methylation profiling in detection of urothelial carcinoma in urine. STUDY DESIGN Thirty-three bladder… 
Highly Cited
2003
Highly Cited
2003
Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia
The role of methylenetetrahydrofolate reductase (MTHFR C677T), glutathione S‐transferases (GSTM1 and GSTT1 null, GSTP1 Ile105Val… 
1999
1999
Quantitative analysis of dose- and time-dependent promotion of four phenotypes of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats.
Determining both the mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) acts as a tumor promoter and the shape of the… 
1998
1998
Vitamin C and aloe vera supplementation protects from chemical hepatocarcinogenesis in the rat.
1994
1994
Different Roles of 8‐Hydroxyguanine Formation and 2‐Thiobarbituric Acid‐reacting Substance Generation in the Early Phase of Liver Carcinogenesis Induced by a Choline‐deficient, l‐Amino Acid‐defined…
The present study was performed to assess the roles of hepatocellular oxidative damage to DNA and constituents other than DNA in… 
1994
1994
The effect of inhibition of glutathione S‐transferase P on the growth of the jurkat human T cell line
To investigate the possible role of glutathione S‐transferase P (GSTP) in carcinogenesis and cell proliferation, ethacrynic acid… 
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