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GSK2269557

National Institutes of Health

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2 relations

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IndazolesOxazoles

Papers overview

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2018
2018
Evaluation of the Safety, Tolerability, and Pharmacokinetics of GSK2269557 (Nemiralisib) Administered Via Dry Powder Inhaler to Healthy Japanese Subjects
The aim of the study was to assess the safety, tolerability, and pharmacokinetics of single and repeat doses of nemiralisib… 
2013
2013
Safety, tolerability and pharmacokinetics (PK) of single and repeat nebulised doses of a novel phosphoinositide 3-kinase δ inhibitor (PI3Kδ), GSK2269557, administered to healthy male subjects in a…
Introduction: GSK2269557 was investigated in a single centre, double blind, placebo controlled trial in healthy male subjects and… 
2013
2013
The effect of a novel phosphoinositide 3-kinase δ inhibitor (PI3Kδ), GSK2269557, on potential biomarkers measured from the lungs of healthy male smokers
Phosphatidylinositol (4,5)-bisphosphate (PIP2) is converted by PI3Kδ into Phosphatidylinositol (3,4,5)-trisphosphate (PIP3). This… 
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