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GSK2194069

National Institutes of Health

Related topics

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2 relations

Broader (2)

PyrrolidinesTriazoles

Papers overview

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2020
2020
Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human…
2018
2018
A new concept in NF2 pharmacotherapy: targeting fatty acid synthesis
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the development of multiple CNS tumors, most… 
2017
2017
Exploring conformation of human fatty acid synthase inhibitors using Replica Exchange Molecular Dynamics
Human fatty acid synthase (hFAS) is a homodimer multienzyme complex involved in the lipogenesis and catalysis of long-chain fatty… 
Review
2015
Review
2015
Molecular Pathways: Fatty Acid Synthase
Therapies that target tumor metabolism represent a new horizon in anticancer therapies. In particular, cancer cells are dependent… 
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