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GSK2194069

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
De novo synthesis of fatty acids is essential to maintain intensive proliferation of cancer cells. Unlike normal cells that… Expand
2019
2019
Toll-like receptor (TLR)/myeloid differentiation primary response protein (MYD88) signaling aggravates sepsis by impairing… Expand
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2018
2018
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the development of multiple CNS tumors, most… Expand
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2017
2017
Human fatty acid synthase (hFAS) is a homodimer multienzyme complex involved in the lipogenesis and catalysis of long-chain fatty… Expand
Review
2015
Review
2015
Therapies that target tumor metabolism represent a new horizon in anticancer therapies. In particular, cancer cells are dependent… Expand
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Highly Cited
2014
Highly Cited
2014
Human fatty acid synthase (hFAS) is a complex, multifunctional enzyme that is solely responsible for the de novo synthesis of… Expand