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GSK1278863

 
National Institutes of Health

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2019
2019
Daprodustat (GSK1278863) is a hypoxia-inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitor in development for treatment of… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Anemia associated with chronic kidney disease (CKD) often requires treatment with recombinant human erythropoietin… Expand
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2016
2016
Hypoxia-inducible factor prolyl hydroxylase inhibitors stabilize levels of hypoxia-inducible factor that upregulate transcription… Expand
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2016
2016
Background: Daprodustat (GSK1278863) is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor being developed for… Expand
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2016
2016
GSK1278863 is an investigative drug under investigation for treatment of anemia associated with chronic kidney disease. Its… Expand
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2016
2016
Drug candidates, which have the potential of enhancing athletic performance represent a risk of being misused in elite sport… Expand
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2016
2016
suggest that oral hypoxia-inducible factor prolyl hydroxylase (PHD) inhibitors might be effective therapies for anaemia in… Expand
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2015
2015
This study was performed to evaluate the pharmacokinetics (PK), pharmacodynamics (PD) and safety of GSK1278863, a novel prolyl… Expand
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2014
2014
Hypoxia inducible factor (HIF) stabilization by HIF-prolyl hydroxylase (PHD) inhibitors may improve ischemic conditions such as… Expand
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2014
2014
Anemia, a frequent complication of chronic kidney disease, is most commonly treated with recombinant human erythropoiesis… Expand
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