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GSK1265744

Known as: GSK744 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2012-2018
02420122018

Related topics

Related topics

2 relations

Broader (1)

Pyridones

Narrower (1)

cabotegravir

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
GSK1265744
Pyridones
cabotegravir

Papers overview

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2015
2015
Antiviral characteristics of GSK1265744, an HIV integrase inhibitor dosed orally or by long-acting injection.
GSK1265744 is a new HIV integrase strand transfer inhibitor (INSTI) engineered to deliver efficient antiviral activity with a… (More)
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2014
2014
GSK1265744 pharmacokinetics in plasma and tissue after single-dose long-acting injectable administration in healthy subjects.
BACKGROUND GSK1265744 (744) is an HIV-1 integrase inhibitor in clinical development as a long-acting (LA) injectable formulation… (More)
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2014
2014
Long-acting HIV drugs advanced to overcome adherence challenge
BOSTON — The results from a particular drug trial presented here last month at the annual Conference on Retroviruses and… (More)
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2014
2014
Pharmacokinetics, safety, and tolerability with repeat doses of GSK1265744 and rilpivirine (TMC278) long-acting nanosuspensions in healthy adults.
OBJECTIVE Pharmacokinetics, safety, and tolerability of GSK1265744 (744) and rilpivirine (RPV) (TMC278) were assessed after… (More)
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2014
2014
Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus.
GSK1265744 (GSK744) is an integrase strand-transfer inhibitor that has been formulated as a long-acting (LA) injectable suitable… (More)
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2013
2013
Lack of pharmacokinetic interaction between rilpivirine and integrase inhibitors dolutegravir and GSK1265744.
Dolutegravir (DTG) and GSK1265744 are HIV integrase inhibitors (INIs) in clinical development. The oral formulation of… (More)
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2013
2013
Pharmacokinetics, safety, and monotherapy antiviral activity of GSK1265744, an HIV integrase strand transfer inhibitor.
BACKGROUND GSK1265744 is an HIV integrase strand transfer inhibitor selected for clinical development. OBJECTIVE This first… (More)
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2013
2013
Effects of etravirine on the pharmacokinetics of the integrase inhibitor S/GSK1265744.
HIV integrase inhibitors such as raltegravir and elvitegravir halt HIV progression, but treatment-emergent resistance and cross… (More)
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2013
2013
Parenteral patent drug S/GSK1265744 has the potential to be an effective agent in pre-exposure prophylaxis against HIV infection.
The continuing HIV epidemic has driven advancements in antiretroviral therapy. New therapeutic targets have been identified over… (More)
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2013
2013
Carbamoyl pyridone HIV-1 integrase inhibitors 3. A diastereomeric approach to chiral nonracemic tricyclic ring systems and the discovery of dolutegravir (S/GSK1349572) and (S/GSK1265744).
We report herein the discovery of the human immunodeficiency virus type-1 (HIV-1) integrase inhibitors dolutegravir (S/GSK1349572… (More)
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