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GSK-7975A

National Institutes of Health

Papers overview

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2019
2019
Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels.
2019
2019
Bronchial Epithelial Calcium Metabolism Impairment in Smokers and COPD: Decreased ORAI3 Signaling.
The airway epithelium represents a fragile environmental interface potentially disturbed by cigarette smoke, the major risk… 
2015
2015
PWE-209 Orai inhibition prevents cytosolic ca2+ overload and acute pancreatitis
Introduction Cytosolic calcium overload triggers pancreatic acinar injury induced by pancreatitis toxins. Sustained Ca2+elevation… 
2014
2014
A protective role for immune suppressive macrophages in acute pancreatitis
2014
2014
GSK-7975A prevents alcoholic acute pancreatitis by blocking store-operated Ca2+ entry
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