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GSK 256066
Known as:
GSK-256066
, GSK256066
National Institutes of Health
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Papers overview
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2020
2020
Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding
Yanaika S. Sabogal Piñeros
,
T. Dekker
,
+6 authors
R. Lutter
Pharmacology Research & Perspectives
2020
Corpus ID: 218874577
Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as…
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2017
2017
P-262 A PDE4 Inhibitor-antibody Conjugate for Treating Ulcerative Colitis
Shan Yu
,
Aaron D. Pearson
,
+15 authors
Matthew S. Tremblay
2017
Corpus ID: 189946041
Background: Although current treatment strategies for ulcerative colitis have been fairly effective, many ulcerative colitis…
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2017
2017
Effect of phosphodiesterase 4B inhibitor GSK256066 on leukocyte/endothelium interactions from chronic obstructive pulmonary disease: an in vitro study
I. Roger
,
A. Morell
,
Pilar Ribera
,
R. Guijarro
,
J. Cortijo
2017
Corpus ID: 79756656
2015
2015
Repurposing Human PDE4 Inhibitors for Neglected Tropical Diseases. Evaluation of Analogs of the Human PDE4 Inhibitor GSK‐256066 as Inhibitors of PDEB1 of Trypanosoma brucei
Stefan O. Ochiana
,
N. Bland
,
L. Settimo
,
R. Campbell
,
M. Pollastri
Chemical Biology and Drug Design
2015
Corpus ID: 1903883
Cyclic nucleotide phosphodiesterases (PDEs) have been identified as important enzyme targets for drug development in both humans…
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2010
2010
A Four-week Randomized Study Of The Safety And Tolerability Of The Inhaled PDE4 Inhibitor GSK256066 In COPD
A. Lazaar
,
Sunil J Mistry
,
C. Barrett
,
Zrinka Lulic-Burns
Asian Test Symposium
2010
Corpus ID: 74786860
2010
2010
Gateways to clinical trials.
A. Tomillero
,
M. A. Moral
Methods and Findings in Experimental and Clinical…
2010
Corpus ID: 29428781
Aclidinium bromide, AE-37, Alemtuzumab, AMA1-C1/ISA 720, Amlodipine besylate/atorvastatin calcium, Arachidonic acid, Arbaclofen…
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2009
2009
In VivoCharacterisation of GSK256066, an Exceptionally High Affinity and Selective PDE4 Inhibitor Suitable for Topical Administration.
R. Knowles
,
DI Ball
,
M. Gascoigne
,
C. Tralau-Stewart
,
A. Nials
Asian Test Symposium
2009
Corpus ID: 76320035
2009
2009
In Vitro Characterisation of GSK256066, an Exceptionally High Affinity and Selective Inhibitor of PDE4 Suitable for Topical Administration.
R. Knowles
,
C. Tralau-Stewart
,
+7 authors
Ramona D. Williamson
Asian Test Symposium
2009
Corpus ID: 76295283
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