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GSK 1838705A
Known as:
GSK-1838705A
, GSK1838705A
National Institutes of Health
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Related topics
2 relations
Broader (2)
Pyrimidines
Pyrroles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
GSK1838705a, an IGF-1R/ALK Inhibitor, Overcomes Resistance to Crizotinib in ALK-Positive ALCL
Wenyu Shi
,
Jian-yong Li
Blood
2019
Corpus ID: 209287007
Anaplastic large cell lymphoma (ALCL) is a type of CD30-expressing non-Hodgkin's lymphoma (NHL), which accounts for 2% to 3% of…
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2018
2018
Strong enhancement by IGF1-R antagonists of hepatocellular carcinoma cell migration inhibition by Sorafenib and/or vitamin K1
R. D'Alessandro
,
M. G. Refolo
,
+4 authors
B. Carr
Cellular Oncology
2018
Corpus ID: 256115165
Emerging evidence indicates that combining Sorafenib with vitamin K1 (VK1) may result in a synergistic inhibition of…
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2016
2016
Abstract 259: Modulation of doxorubicin actions on HCC cells by insulin-like growth factor-I
B. Carr
,
M. G. Refolo
,
R. D'Alessandro
,
N. Carella
,
C. Messa
,
A. Cavallini
2016
Corpus ID: 79263771
Tumor microenvironment is increasingly understood to influence tumor biology in many tumor types, including HCC. We recently…
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2015
2015
GSK1838705A, an IGF-1R inhibitor, inhibits glioma cell proliferation and suppresses tumor growth in vivo
Xiaoping Zhou
,
Fazheng Shen
,
+6 authors
Baozhe Jin
Molecular Medicine Reports
2015
Corpus ID: 17692001
Glioma is a type of primary malignant tumor of the central nervous system in humans. At present, standard treatment involves…
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2015
2015
Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1
Catia Lippolis
,
M. G. Refolo
,
+4 authors
B. Carr
Journal of experimental & clinical cancer…
2015
Corpus ID: 255981458
Blood platelet numbers are correlated with growth and aggressiveness of several tumor types, including hepatocellular carcinoma…
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2009
2009
Abstract #1740: Characterization of GSK1838705A, a small molecule inhibitor of the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase that delays growth of IGF-1R-dependent tumors…
S. Rabindran
,
P. Sabbatini
,
+17 authors
Rakesh Kumar
2009
Corpus ID: 83853444
The insulin-like growth factor-1 receptor (IGF-1R) signaling pathway is activated in various tumors and inhibition of IGF-1R…
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