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GSK 1034702

Known as: GSK-1034702, GSK1034702 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
0120132017

Related topics

Related topics

1 relation

Broader (1)

Benzimidazoles

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
GSK 1034702
Benzimidazoles

Papers overview

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2017
2017
Retrospective use of PBPK modelling to understand a clinical drug-drug interaction between dextromethorphan and GSK1034702.
1. In a clinical trial, a strong drug-drug interaction (DDI) was observed between dextromethorphan (DM, the object or victim drug… (More)
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2014
2014
An evaluation of the brain distribution of [11C]GSK1034702, a muscarinic-1 (M1) positive allosteric modulator in the living human brain using positron emission tomography
BACKGROUND The ability to quantify the capacity of a central nervous system (CNS) drug to cross the human blood-brain barrier… (More)
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2013
2013
The potent M1 receptor allosteric agonist GSK1034702 improves episodic memory in humans in the nicotine abstinence model of cognitive dysfunction.
Episodic memory deficits are a core feature of neurodegenerative disorders. Muscarinic M(1) receptors play a critical role in… (More)
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