GS-6620
National Institutes of Health
Papers overview
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Delivery of pharmacologically active nucleoside triphosphate analogs to sites of viral infection is challenging. In prior work we…
Background GS-9256 is an inhibitor of HCV NS3 protease with a macrocyclic structure and novel phosphinic acid pharmacophore…
Two new C-nucleoside analogues, BCX4430, an imino-C-nucleoside, and GS-6620, a phosphoramidate derivative of 1'-cyano-2'-C-methyl…
ABSTRACT As a class, nucleotide inhibitors (NIs) of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent RNA…
Introduction: About 150 million people worldwide are estimated to be chronically infected with the hepatitis C virus (HCV…
ABSTRACT GS-9451 is a selective hepatitis C virus (HCV) NS3 protease inhibitor in development for the treatment of genotype 1…