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GRB7 gene

Known as: Growth Factor Receptor-Bound Protein 7 Gene, GRB7, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 
This gene is involved in signal transduction and protein binding.
National Institutes of Health

Related topics

Related topics

3 relations
Growth Factor Receptor-Bound Protein 7Signal Transductionprotein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Correction: Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells
2013
2013
Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?
Grb7 is an adapter protein involved in the propagation of signals in cancer cell migration and proliferation, and is thus a… 
2012
2012
Expression screening of 17q12–21 amplicon reveals GRB7 as an ERBB2‐dependent oncogene
2012
2012
Abstract 2159: Targeting GRB7/ERK/FOXM1 signaling cascade is a promising therapeutic approach in ovarian cancer
Ovarian cancer is a higly mortal disease with poor prognosis and especially in high grade tumor. Emerging evidence has reported… 
2011
2011
Abstract 255: GRB7 – a novel target in triple-negative breast cancer
Triple-negative breast tumors lack expression of estrogen and progesterone receptors and HER2, rendering them non-responsive to… 
2010
2010
Kappa opioid receptor contributes to EGF-stimulated neurite extension in development
Epidermal growth factor (EGF), a mitogen, also stimulates neurite extension during development, but the underlying mechanism is… 
2009
2009
GRB7-dependent pathways are potential therapeutic targets in triple-negative breast cancer.
CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts Abstract #25 Background: Breast cancer lacking expression of the… 
2009
2009
GRB7 and HER2 protein overexpression and breast cancer outcome.
11102 Background: The growth factor receptor-bound protein-7 gene (GRB7) encodes a multi-domain signal transduction molecule and… 
2006
2006
Molecular Dissection of 17q12 Amplicon in Upper Gastrointestinal Adenocarcinomas
DNA amplification at 17q is frequently detected in upper gastrointestinal adenocarcinomas (UGC; stomach and esophagus). In this… 
2003
2003
MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
MYC, ERBB2, MET, FGFR2, CCNE1, MYCN, WNT2, CD44, MDM2, NCOA3, IQGAP1 and STK6 loci are amplified in human gastric cancer. It has… 
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