Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,179,445 papers from all fields of science
Search
Sign In
Create Free Account
GRB14 protein, human
Known as:
GRB14
, Growth Factor Receptor-Bound Protein 14
, growth factor receptor-bound protein 14, human
Member of the GRB7 family of adapter proteins; identified as a partner of the insulin receptor where it acts as a modulator of insulin signaling…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
7 relations
Broader (1)
Adaptor Proteins, Signal Transducing
Adaptor Signaling Protein Gene
GRB14 gene
Signal Transduction
Signaling Pathway Gene
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle.
Jung-Jun Park
,
Jason R. Berggren
,
M. Hulver
,
J. Houmard
,
E. Hoffman
Physiological genomics
2006
Corpus ID: 14489229
Obesity is associated with insulin resistance in skeletal muscle; accordingly, weight loss dramatically improves insulin action…
Expand
Review
2005
Review
2005
Grb10 and Grb14: enigmatic regulators of insulin action--and more?
L. J. Holt
,
K. Siddle
The Biochemical journal
2005
Corpus ID: 32732996
The Grb proteins (growth factor receptor-bound proteins) Grb7, Grb10 and Grb14 constitute a family of structurally related…
Expand
Highly Cited
2005
Highly Cited
2005
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14.
R. Depetris
,
Junjie Hu
,
I. Gimpelevich
,
L. J. Holt
,
R. Daly
,
S. Hubbard
Molecular cell
2005
Corpus ID: 34940882
2004
2004
SAXS study of the PIR domain from the Grb14 molecular adaptor: a natively unfolded protein with a transient structure primer?
K. Moncoq
,
I. Broutin
,
C. Craescu
,
P. Vachette
,
A. Ducruix
,
D. Durand
Biophysical journal
2004
Corpus ID: 16197849
Grb14 belongs to the Grb7 family of adapters and was identified as a negative regulator of insulin signal transduction. Between…
Expand
Highly Cited
2004
Highly Cited
2004
Improved glucose homeostasis and enhanced insulin signalling in Grb14‐deficient mice
G. Cooney
,
R. Lyons
,
+7 authors
R. Daly
The EMBO journal
2004
Corpus ID: 36717287
Gene targeting was used to characterize the physiological role of growth factor receptor‐bound (Grb)14, an adapter‐type…
Expand
Highly Cited
2002
Highly Cited
2002
Identification of Novel Non-phosphorylated Ligands, Which Bind Selectively to the SH2 Domain of Grb7*
S. Pero
,
L. Oligino
,
+5 authors
D. Krag
The Journal of Biological Chemistry
2002
Corpus ID: 23083451
Grb7 is an adapter-type signaling protein, which is recruited via its SH2 domain to a variety of receptor tyrosine kinases (RTKs…
Expand
Highly Cited
2001
Highly Cited
2001
Identification of a Novel Human Tankyrase through Its Interaction with the Adaptor Protein Grb14*
R. Lyons
,
R. Deane
,
+5 authors
R. Daly
The Journal of Biological Chemistry
2001
Corpus ID: 11339947
Tankyrase is an ankyrin repeat-containing poly(ADP-ribose) polymerase originally isolated as a binding partner for the telomeric…
Expand
Highly Cited
1998
Highly Cited
1998
Interaction of the Grb10 Adapter Protein with the Raf1 and MEK1 Kinases*
A. Nantel
,
K. Mohammad-Ali
,
Jennifer Sherk
,
B. Posner
,
David Y. Thomas
The Journal of Biological Chemistry
1998
Corpus ID: 31320399
Grb10 and its close homologues Grb7 and Grb14, belong to a family of adapter proteins characterized by a proline-rich region, a…
Expand
Highly Cited
1998
Highly Cited
1998
Grb10 Interacts Differentially with the Insulin Receptor, Insulin-like Growth Factor I Receptor, and Epidermal Growth Factor Receptor via the Grb10 Src Homology 2 (SH2) Domain and a Second Novel…
Weimin He
,
D. Rose
,
J. Olefsky
,
T. Gustafson
The Journal of Biological Chemistry
1998
Corpus ID: 24104647
The Grb10 protein appears to be an adapter protein of unknown function that has been implicated in insulin receptor (IR…
Expand
Highly Cited
1998
Highly Cited
1998
Identification of the Rat Adapter Grb14 as an Inhibitor of Insulin Actions*
A. Kasus‐Jacobi
,
D. Perdereau
,
+5 authors
A. Burnol
The Journal of Biological Chemistry
1998
Corpus ID: 13343031
We cloned by interaction with the β-subunit of the insulin receptor the rat variant of the human adapter Grb14 (rGrb14). rGrb14…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE