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GRB14 protein, human

Known as: GRB14, Growth Factor Receptor-Bound Protein 14, growth factor receptor-bound protein 14, human 
Member of the GRB7 family of adapter proteins; identified as a partner of the insulin receptor where it acts as a modulator of insulin signaling… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (1)

Adaptor Proteins, Signal Transducing
Adaptor Signaling Protein GeneGRB14 geneSignal TransductionSignaling Pathway Gene

Papers overview

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2014
2014
Assessment of insulin proteolysis in rat liver endosomes: its relationship to intracellular insulin signaling.
2014
2014
Analysis of mRNA-expression profiles of GRB14 in human subcutaneous and visceral adipose tissue
2010
2010
Tyrosine phosphorylation of Grb14 by Tie2
BackgroundGrowth factor receptor bound (Grb) proteins 7, 10 and 14 are a family of structurally related multi-domain adaptor… 
2009
2009
Endosomal proteolysis of internalised [ArgA0]-human insulin at neutral pH generates the mature insulin peptide in rat liver in vivo
Aims/hypothesisA proteolysis study of human monoarginyl-insulin ([ArgA0]-HI) and diarginyl-insulin ([ArgB31-ArgB32]-HI) within… 
2008
2008
Dual effect of the adapter Grb14 on insulin action in primary mouse hepatocytes
2005
2005
FGF receptor phosphotyrosine 766 is a target for Grb14 to inhibit MDA-MB-231 human breast cancer cell signaling.
BACKGROUND Fibroblast growth factors receptors (FGFRs) are involved in estrogen-independent breast cancer cell growth. Grbl4, a… 
2005
2005
Lipid-protein interactions of growth factor receptor-bound protein 14 in insulin receptor signaling.
Many retinal degenerative diseases show an early loss of rod cells followed by cone cells. In these degenerations the… 
2005
2005
Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7‐SH2/erbB2 peptide complex
Grb7 is a member of the Grb7 family of proteins, which also includes Grb10 and Grb14. All three proteins have been found to be… 
2004
2004
Solution structure of the human Grb14–SH2 domain and comparison with the structures of the human Grb7–SH2/erbB2 peptide complex and human Grb10–SH2 domain
Grb14 is an adapter protein that is known to be overexpressed in estrogen receptor positive breast cancers, and in a number of… 
Highly Cited
2001
Highly Cited
2001
Identification of a Novel Human Tankyrase through Its Interaction with the Adaptor Protein Grb14*
Tankyrase is an ankyrin repeat-containing poly(ADP-ribose) polymerase originally isolated as a binding partner for the telomeric… 
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