GRB10 gene

Known as: GRB10, MEG1, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10 
This gene is involved in signal transduction. It plays a role in the regulation of both apoptosis and cell proliferation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
02419942017

Papers overview

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2009
2009
Mice with maternal duplication of proximal Chromosome 11 (MatDp(prox11)), where Meg1/Grb10 is located, exhibit pre- and postnatal… (More)
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Highly Cited
2003
Highly Cited
2003
To investigate the function of the Grb10 adapter protein, we have generated mice in which the Grb10 gene was disrupted by a gene… (More)
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2003
2003
The imprinted mouse gene Meg1/Grb10 is expres sed from maternal alleles in almost all tissues and organs, except in the brain… (More)
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Highly Cited
2003
Highly Cited
2003
Grb10/GRB10 encodes a cytoplasmic adapter protein which modulates coupling of a number of cell surface receptor tyrosine kinases… (More)
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2002
2002
Maternal duplication of human 7p11.2-p13 has been associated with Silver-Russell syndrome (SRS) in two familial cases. GRB10 is… (More)
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2001
2001
The GRB10 gene encodes a growth suppressor and maps to human chromosome 7p11.2-p13. Maternal duplication (matdup) of this region… (More)
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Highly Cited
2000
Highly Cited
2000
As part of a systematic screen for novel imprinted genes of human chromosome 7 we have investigated GRB10, which belongs to a… (More)
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2000
2000
Silver-Russell syndrome (SRS) is characterized by pre- and postnatal growth failure and other dysmorphic features. The syndrome… (More)
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2000
2000
Documentation of maternal uniparental disomy of chromosome 7 in 10% of patients with Russell-Silver syndrome (RSS), characterized… (More)
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1998
1998
In a systematic screen for maternally expressed imprinted genes using subtraction hybridization with androgenetic and normal… (More)
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