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GPD-1116

National Institutes of Health

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Naphthyridines

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2008
2008
Phosphodiesterase 4 inhibitor GPD-1116 markedly attenuates the development of cigarette smoke-induced emphysema in senescence-accelerated mice P1 strain.
Phosphodiesterase 4 (PDE4) is an intracellular enzyme specifically degrading cAMP, a second messenger exerting inhibitory effects… 
2007
2007
PDE4 inhibitor (GPD-1116) prevents senescence accelerated mice P1 strain (SAMP1) from developing cigarette-smoke-induced emphysema
2007
2007
PDE4 inhibitor (GPD-1116) prevents senescence-accelerated mice P1 strain (SAMP1) from developing cigarette smoke-induced emphysema.(Annual Report from the Division of Biomedical Research Resources…
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