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GPA33 gene

Known as: A33, CELL SURFACE ANTIGEN A33, Glycoprotein A33 (Transmembrane) Gene 
This gene plays a role in transcription and is a member of the immunoglobulin superfamily.
National Institutes of Health

Papers overview

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2020
2020
Key Points Thymic-derived Tregs are the most attractive cell type for adoptive cell therapy. Tregs that express the surface… 
2018
2018
We have developed MGD007 (anti-glycoprotein A33 x anti-CD3), a DART protein designed to redirect T cells to target gpA33… 
2018
2018
In recent reports, we have shown that optimized pretargeted radioimmunotherapy (PRIT) based on molecularly engineered antibody… 
2018
2018
Despite progress in the treatment of colorectal cancer, curing metastatic colorectal cancer remains a major unmet medical need… 
2017
2017
Radioimmunotherapy of solid tumors using antibody-targeted radionuclides has been limited by low therapeutic indices (TIs). We… 
2015
2015
PurposeGPA33 is a colorectal cancer (CRC) antigen with unique retention properties after huA33-mediated tumor targeting. We… 
2012
2012
A single-chain fusion protein that directed the cytolytic activity of α-sarcin to A33 tumor antigen expressing cells was… 
2012
2012
Within the last 10 years, the use of different RNases as therapeutic agents for various diseases has been pursued. Furthermore… 
2009
2009
The glycoprotein A33 (GPA33) is a colon cancer antigen. Phase I trials with 131I and 125I monoclonal antibody A33 in colon…