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GPA33 gene

Known as: A33, CELL SURFACE ANTIGEN A33, Glycoprotein A33 (Transmembrane) Gene 
This gene plays a role in transcription and is a member of the immunoglobulin superfamily.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Selective photokilling of colorectal tumors by near-infrared photoimmunotherapy with a GPA33-targeted single-chain antibody variable fragment conjugate.
Antibody-based near-infrared photoimmunotherapy (NIR-PIT) is an attractive strategy for cancer treatment. Tumor cells can be… 
2016
2016
Science Briefs from the SNMMI Annual Meeting.
Theranostic RIT in CRC Researchers from Memorial Sloan– Kettering Cancer Center (New York, NY) and the Massachusetts Institute of… 
2015
2015
Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts
Tagging of RNases, such as the ribotoxin α-sarcin, with the variable domains of antibodies directed to surface antigens that are… 
2015
2015
CF750-A33scFv-Fc-Based Optical Imaging of Subcutaneous and Orthotopic Xenografts of GPA33-Positive Colorectal Cancer in Mice
Antibody-based imaging agents are attractive as adjuvant diagnostic tools for solid tumors. GPA33 is highly expressed in most… 
2015
2015
A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations
ABSTRACT Activation of the Wnt/β-catenin pathway occurs in the vast majority of colorectal cancers. However, the outcome of the… 
2012
2012
Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells
Within the last 10 years, the use of different RNases as therapeutic agents for various diseases has been pursued. Furthermore… 
2011
2011
Charakterisierung von gpA33 und Eignung als Antikörper-Target
2009
2009
KLF 4-dependent , PPAR γ-induced expression of GPA 33 in colon cancer cell lines
The glycoprotein A33 (GPA33) is a colon cancer antigen. Phase I trials with 131I and 125I monoclonal antibody A33 in colon… 
2008
2008
Surface expression of gpA33 is dependent on culture density and cell-cycle phase and is regulated by intracellular traffic rather than gene transcription.
The cell-surface marker, gpA33, a new member of the immunoglobulin superfamily, is expressed by gastrointestinal cells and by 95… 
1992
1992
Analysis of peptidic epitopes recognized by the three monoclonal antibodies specific for the same region of glycophorin A but showing different properties.
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