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National Institutes of Health
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Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity.
Brian S Safina
Zachary K Sweeney
Bioorganic & medicinal chemistry letters
Corpus ID: 1228323
In an effort to identify potent and isoform selective inhibitors of PI3Kδ, GNE-293 (34) was identified. Inhibitor 2 was found to…
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