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GMP reductase

Known as: Guanosine 5'-Phosphate Reductase, Guanylate Reductase, Oxidoreductase, Guanosine 5'-Monophosphate 
An enzyme that catalyzes the reversible oxidation of inosine 5'-phosphate (IMP) to guanosine 5'-phosphate (GMP) in the presence of AMMONIA and NADP… 
National Institutes of Health

Related topics

Related topics

8 relations
GMPR geneIn BloodProcess of secretionantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Transforming mutations of RAC guanosine triphosphatases in human cancers
Members of the RAS superfamily of small guanosine triphosphatases (GTPases) transition between GDP-bound, inactive and GTP-bound… 
2010
2010
Polymorphic Variation of the Guanosine Triphosphate Cyclohydrolase 1 Gene Predicts Outcome in Patients Undergoing Surgical Treatment for Lumbar Degenerative Disc Disease
Study Design. Prospective observational study. Objective. To determine whether polymorphic variations of the guanosine… 
Highly Cited
2008
Highly Cited
2008
Reduction of oxidative stress marker levels by anti-TNF-alpha antibody, infliximab, in patients with rheumatoid arthritis.
OBJECTIVE The aim of this study was to evaluate the effects of anti-TNF-alpha antibody, infliximab, on oxidative stress markers… 
Highly Cited
2007
Highly Cited
2007
Etanercept reduces the oxidative stress marker levels in patients with rheumatoid arthritis
This study was performed to evaluate the effects of the TNF-α inhibitor etanercept on oxidation stress markers representing DNA… 
Highly Cited
2002
Highly Cited
2002
Mitochondrial DNA depletion
Background: The mitochondrial DNA (mtDNA) depletion syndrome (MDS) is an autosomal recessive disorder of early childhood… 
Highly Cited
1998
Highly Cited
1998
Ribavirin in hepatitis C related cryoglobulinemia.
OBJECTIVE An open, uncontrolled trial of ribavirin, an oral guanosine nucleoside analog for treatment of hepatitis C, in patients… 
Review
1996
Review
1996
Mycophenolate mofetil. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in renal transplantation.
Mycophenolate mofetil is an ester prodrug of the active immunosuppressant mycophenolic acid. It is a noncompetitive, selective… 
Highly Cited
1994
Highly Cited
1994
Mechanisms for protective effects of free radical scavengers on gentamicin-mediated nephropathy in rats.
Studies were performed to examine the mechanisms for the protective effects of free radical scavengers on gentamicin (GM… 
Highly Cited
1993
Highly Cited
1993
Whole-cell recording of anoxic effects on hippocampal neurons in slices.
1. In 400-microns-thick slices from young adult Sprague-Dawley rats, CA1 pyramidal layer neurons were studied by the whole-cell… 
Highly Cited
1971
Highly Cited
1971
Inhibition of replication in functional mouse adrenal tumor cells by adrenocorticotropic hormone mediated by adenosine 3':5'-cyclic monophosphate.
Adrenocorticotropic hormone (ACTH) inhibited replication in functional adrenal tumor cells with a concomitant stimulation of… 
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