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GLTSCR2 wt Allele

Known as: Glioma Tumor Suppressor Candidate Region Gene 2 wt Allele, PICT-1, PICT1 
Human GLTSCR2 wild-type allele is located in the vicinity of 19q13.3 and is approximately 12 kb in length. This allele, which encodes glioma tumor… 
National Institutes of Health

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Related topics

4 relations
19q13.3Homo sapiensProtein phosphorylation

Broader (1)

GLTSCR2 gene

Papers overview

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2018
2018
Abnormal Expression of PICT-1 and Its Codon 389 Polymorphism Is a Risk Factor for Human Endometrial Cancer
Objective: The protein interacting with carboxyl terminus-1 (PICT-1) gene has been implicated as a tumor suppressor gene, and its… 
2017
2017
The protein interacting with carboxyl terminus‐1 codon 389 polymorphism impairs protein interacting with carboxyl terminus‐1 function and is a risk factor for uterine cervical cancer
PICT‐1 is a nucleolar protein with various tumor suppressor functions. Recently, PICT‐1 expression was reported to be… 
2017
2017
Stabilization mechanism for PICT1 oncoprotein
2016
2016
PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway
PICT-1 is an essential ribosome biogenesis factor whose loss induces p53 accumulation and apoptosis. Here, we show that DNA… 
2016
2016
Abstract 1168: The codon 389 polymorphism of PICT-1 is a risk factor for human cervical cancer
2014
2014
The nucleolar PICT-1/GLTSCR2 protein forms homo-oligomers.
2013
2013
Clinical Significance of PICT1 in Patients of Hepatocellular Carcinoma with Wild-Type TP53
BackgroundTP53 is one of the most widely known cancer suppressor genes. Mutations in TP53 are ubiquitously observed in almost all… 
2012
2012
Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences
The human glioma tumor suppressor candidate region 2 gene product, GLTSCR2, also called ‘protein interacting with carboxyl… 
2011
2011
Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus.
2009
2009
GLTSCR2/PICT-1, a Putative Tumor Suppressor Gene Product, Induces the Nucleolar Targeting of the Kaposi's Sarcoma-Associated Herpesvirus KS-Bcl-2 Protein
ABSTRACT KS-Bcl-2, encoded by Kaposi's sarcoma-associated herpesvirus (KSHV), is a structural and functional homologue of the Bcl… 
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