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GLTSCR2 wt Allele

Known as: Glioma Tumor Suppressor Candidate Region Gene 2 wt Allele, PICT-1, PICT1 
Human GLTSCR2 wild-type allele is located in the vicinity of 19q13.3 and is approximately 12 kb in length. This allele, which encodes glioma tumor… 
National Institutes of Health

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Related topics

4 relations
19q13.3Homo sapiensProtein phosphorylation

Broader (1)

GLTSCR2 gene

Papers overview

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2016
2016
PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway
PICT-1 was originally identified as a tumor suppressor. Here, we found that PICT-1 overexpression triggered pro-death autophagy… 
Highly Cited
2015
Highly Cited
2015
The Exosome Is Recruited to RNA Substrates through Specific Adaptor Proteins
2013
2013
PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression
Background:The TP53 pathway is frequently inactivated in human cancers. PICT1 (also known as GLTSCR2) is a novel regulator of the… 
Review
2012
Review
2012
A new PICTure of nucleolar stress
Cell growth demands new protein synthesis, which requires nucleolar ribosomal functions. Ribosome biogenesis consumes a large… 
2012
2012
Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences
The human glioma tumor suppressor candidate region 2 gene product, GLTSCR2, also called ‘protein interacting with carboxyl… 
2011
2011
Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus.
2011
2011
DePICTing p53 activation: a new nucleolar link to cancer.
2009
2009
GLTSCR2/PICT-1, a Putative Tumor Suppressor Gene Product, Induces the Nucleolar Targeting of the Kaposi's Sarcoma-Associated Herpesvirus KS-Bcl-2 Protein
ABSTRACT KS-Bcl-2, encoded by Kaposi's sarcoma-associated herpesvirus (KSHV), is a structural and functional homologue of the Bcl… 
Highly Cited
2006
Highly Cited
2006
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation.
The tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) regulates diverse cellular functions by… 
Highly Cited
2004
Highly Cited
2004
Regulation of PTEN Phosphorylation and Stability by a Tumor Suppressor Candidate Protein*♦
The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is… 
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