Skip to search formSkip to main contentSkip to account menu

GLTSCR2 gene

Known as: GLTSCR2, PICT-1, PICT1 
This gene plays a role in the regulation of protein phosphorylation and turnover.
National Institutes of Health

Related topics

Related topics

3 relations
GLTSCR2 protein, humanProtein phosphorylation

Narrower (1)

GLTSCR2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abnormal Expression of PICT-1 and Its Codon 389 Polymorphism Is a Risk Factor for Human Endometrial Cancer
Objective: The protein interacting with carboxyl terminus-1 (PICT-1) gene has been implicated as a tumor suppressor gene, and its… 
2017
2017
The protein interacting with carboxyl terminus‐1 codon 389 polymorphism impairs protein interacting with carboxyl terminus‐1 function and is a risk factor for uterine cervical cancer
PICT‐1 is a nucleolar protein with various tumor suppressor functions. Recently, PICT‐1 expression was reported to be… 
2017
2017
Abstract 2574: The PICT-1 is required for USP7 to effectively stabilize p53 protein, and codon 389 polymorphism is a risk factor for ovarian cancer
The ovarian cancers causes the deaths of more than 100,000 women per year worldwide, and it is a complex disease, with multiple… 
2016
2016
PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway
PICT-1 was originally identified as a tumor suppressor. Here, we found that PICT-1 overexpression triggered pro-death autophagy… 
2016
2016
PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway
PICT-1 is an essential ribosome biogenesis factor whose loss induces p53 accumulation and apoptosis. Here, we show that DNA… 
2013
2013
Clinical Significance of PICT1 in Patients of Hepatocellular Carcinoma with Wild-Type TP53
BackgroundTP53 is one of the most widely known cancer suppressor genes. Mutations in TP53 are ubiquitously observed in almost all… 
2012
2012
Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences
The human glioma tumor suppressor candidate region 2 gene product, GLTSCR2, also called ‘protein interacting with carboxyl… 
2011
2011
Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus.
Highly Cited
2006
Highly Cited
2006
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation.
The tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) regulates diverse cellular functions by… 
Highly Cited
2004
Highly Cited
2004
Regulation of PTEN Phosphorylation and Stability by a Tumor Suppressor Candidate Protein*♦
The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)