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Objective: The protein interacting with carboxyl terminus-1 (PICT-1) gene has been implicated as a tumor suppressor gene, and its… Expand PICT‐1 is a nucleolar protein with various tumor suppressor functions. Recently, PICT‐1 expression was reported to be… Expand The ovarian cancers causes the deaths of more than 100,000 women per year worldwide, and it is a complex disease, with multiple… Expand PICT-1 was originally identified as a tumor suppressor. Here, we found that PICT-1 overexpression triggered pro-death autophagy… Expand PICT-1 is an essential ribosome biogenesis factor whose loss induces p53 accumulation and apoptosis. Here, we show that DNA… Expand BackgroundTP53 is one of the most widely known cancer suppressor genes. Mutations in TP53 are ubiquitously observed in almost all… Expand The human glioma tumor suppressor candidate region 2 gene product, GLTSCR2, also called ‘protein interacting with carboxyl… Expand Moesin-ezrin-radixin-like protein (merlin) has long been considered a unique tumour suppressor that inhibits mitogenic signalling… Expand The tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) regulates diverse cellular functions by… Expand The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is… Expand