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GLTSCR2 gene
Known as:
GLTSCR2
, PICT-1
, PICT1
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This gene plays a role in the regulation of protein phosphorylation and turnover.
National Institutes of Health
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Related topics
Related topics
3 relations
GLTSCR2 protein, human
Protein phosphorylation
Narrower (1)
GLTSCR2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abnormal Expression of PICT-1 and Its Codon 389 Polymorphism Is a Risk Factor for Human Endometrial Cancer
M. Yoshimoto
,
A. Tokuda
,
K. Nishiwaki
,
K. Sengoku
,
Y. Yaginuma
Oncology
2018
Corpus ID: 4603043
Objective: The protein interacting with carboxyl terminus-1 (PICT-1) gene has been implicated as a tumor suppressor gene, and its…
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2017
2017
The protein interacting with carboxyl terminus‐1 codon 389 polymorphism impairs protein interacting with carboxyl terminus‐1 function and is a risk factor for uterine cervical cancer
M. Yoshimoto
,
A. Tokuda
,
K. Nishiwaki
,
K. Sengoku
,
Y. Yaginuma
Molecular Carcinogenesis
2017
Corpus ID: 13095220
PICT‐1 is a nucleolar protein with various tumor suppressor functions. Recently, PICT‐1 expression was reported to be…
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2017
2017
Abstract 2574: The PICT-1 is required for USP7 to effectively stabilize p53 protein, and codon 389 polymorphism is a risk factor for ovarian cancer
M. Yoshimoto
,
A. Tokuda
,
Y. Yaginuma
2017
Corpus ID: 79568970
The ovarian cancers causes the deaths of more than 100,000 women per year worldwide, and it is a complex disease, with multiple…
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2016
2016
PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway
Hongbo Chen
,
Yanhong Duo
,
+8 authors
Laiqiang Huang
OncoTarget
2016
Corpus ID: 3505191
PICT-1 was originally identified as a tumor suppressor. Here, we found that PICT-1 overexpression triggered pro-death autophagy…
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2016
2016
PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway
Hongbo Chen
,
Liqiao Han
,
+10 authors
Laiqiang Huang
OncoTarget
2016
Corpus ID: 3490924
PICT-1 is an essential ribosome biogenesis factor whose loss induces p53 accumulation and apoptosis. Here, we show that DNA…
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2013
2013
Clinical Significance of PICT1 in Patients of Hepatocellular Carcinoma with Wild-Type TP53
M. Ishibashi
,
R. Kogo
,
+17 authors
K. Mimori
Annals of Surgical Oncology
2013
Corpus ID: 20157413
BackgroundTP53 is one of the most widely known cancer suppressor genes. Mutations in TP53 are ubiquitously observed in almost all…
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2012
2012
Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences
Inna Kalt
,
Ayelet Levy
,
Tatyana Borodianskiy-Shteinberg
,
R. Sarid
PLoS ONE
2012
Corpus ID: 921096
The human glioma tumor suppressor candidate region 2 gene product, GLTSCR2, also called ‘protein interacting with carboxyl…
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2011
2011
Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus.
Hongbo Chen
,
Lin Mei
,
+7 authors
Laiqiang Huang
International Journal of Biochemistry and Cell…
2011
Corpus ID: 24314043
Highly Cited
2006
Highly Cited
2006
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation.
F. Okahara
,
K. Itoh
,
A. Nakagawara
,
M. Murakami
,
Y. Kanaho
,
T. Maehama
Molecular Biology of the Cell
2006
Corpus ID: 23852612
The tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) regulates diverse cellular functions by…
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Highly Cited
2004
Highly Cited
2004
Regulation of PTEN Phosphorylation and Stability by a Tumor Suppressor Candidate Protein*♦
F. Okahara
,
H. Ikawa
,
Y. Kanaho
,
T. Maehama
Journal of Biological Chemistry
2004
Corpus ID: 46237707
The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is…
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