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GINS4 gene

Known as: SLD5, S. CEREVISIAE, HOMOLOG OF, SLD5, GINS4 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
GINS complex subunit 4, a prognostic biomarker and reversely mediated by Krüppel‐like factor 4, promotes the growth of colorectal cancer
GINS complex subunit 4 (GINS4) is essential for DNA replication initiation and elongation in the G1/S phase cell cycle in… 
Highly Cited
2019
Highly Cited
2019
The novel GINS4 axis promotes gastric cancer growth and progression by activating Rac1 and CDC42
Rationale: As a component of GINS complex, GINS4 is essential for initiating DNA replication and elongation of the cell cycle G1… 
2019
2019
LSH interacts with and stabilizes GINS4 transcript that promotes tumourigenesis in non-small cell lung cancer
Elucidating mechanisms in oncogenes and epigenetic modifiers are needed to gain insights into the etiology and treatment of… 
2018
2018
Visualization of Proliferative Vascular Endothelial Cells in Tumors in Vivo by Imaging Their Partner of Sld5-1 Promoter Activity.
2016
2016
Regulation of SLD5 gene expression by miR-370 during acute growth of cancer cells
SLD5 is a member of the GINS complex, essential for DNA replication in eukaryotes. It has been reported that SLD5 is involved in… 
2016
2016
GINS complex protein Sld5 recruits SIK1 to activate MCM helicase during DNA replication.
2014
2014
DNA Damage Enhanced by the Attenuation of SLD5 Delays Cell Cycle Restoration in Normal Cells but Not in Cancer Cells
SLD5 is a member of the GINS complex composed of PSF1, PSF2, PSF3 and SLD5, playing a critical role in the formation of the DNA… 
2013
2013
Requirement of SLD5 for Early Embryogenesis
SLD5 forms a GINS complex with PSF1, PSF2 and PSF3, which is essential for the initiation of DNA replication in lower eukaryotes… 
Review
2010
Review
2010
The initiation step of eukaryotic DNA replication.
Eukaryotic initiation of DNA replication is a tightly regulated process. In the yeasts, S-phase-specific cyclin Cdk1 complex as… 
2010
2010
Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2–7 complex
Mcm2–7 is recruited to eukaryotic origins of DNA replication by origin recognition complex, Cdc6 and Cdt1 thereby licensing the… 
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