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GIMAP5 gene
Known as:
IMAP3
, GTPase, IMAP family member 5
, IAN4L1
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National Institutes of Health
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Related topics
Related topics
1 relation
GIMAP1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Gimap3 and Gimap5 cooperate to maintain T‐cell numbers in the mouse
K. Yano
,
C. Carter
,
+7 authors
Y. Takahama
European journal of immunology
2014
Corpus ID: 13730361
Gimap3 (IAN4) and Gimap5 (IAN5) are highly homologous GTP‐binding proteins of the Gimap family. Gimap3 and Gimap5, whose…
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2011
2011
Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells
Y. Chen
,
M. Yu
,
+4 authors
D. Wang
The Journal of experimental medicine
2011
Corpus ID: 3104106
HSCs lacking the guanosine nucleotide-binding protein Gimap5, which stabilizes expression of the Mcl-1 Bcl2 family protein…
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2010
2010
The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein.
Vivian Wy Wong
,
Amy Saunders
,
+6 authors
G. Butcher
Self/nonself
2010
Corpus ID: 24502379
A mutation in the rat GIMAP5 gene predisposes for autoimmunity, most famously in the BB rat model of autoimmune type 1 diabetes…
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2009
2009
Loss of GIMAP5 (GTPase of immunity-associated nucleotide binding protein 5) impairs calcium signaling in rat T lymphocytes.
S. Ilangumaran
,
Melissa Forand-Boulerice
,
+7 authors
S. Ramanathan
Molecular immunology
2009
Corpus ID: 22826223
The recessive lyp allele, which harbors a defective gimap5 (GTPase of immunity-associated nucleotide binding protein 5) gene…
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2009
2009
IAN5 polymorphisms are associated with systemic lupus erythematosus
M. K. Lim
,
D. H. Sheen
,
+5 authors
S. C. Shim
Lupus
2009
Corpus ID: 36617048
Systemic lupus erythematosus (SLE) is a representative autoimmune disease, which is frequently associated with lymphopenia…
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Highly Cited
2008
Highly Cited
2008
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5.
Ryan D Schulteis
,
Haiyan Chu
,
+15 authors
H. Weiler
Blood
2008
Corpus ID: 3153843
The loss of Gimap5 (GTPase of the immune-associated protein 5) gene function is the underlying cause of lymphopenia and…
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2007
2007
Both Gimap5 and the diabetogenic BBDP allele of Gimap5 induce apoptosis in T cells.
U. Dalberg
,
H. Markholst
,
L. Hornum
International immunology
2007
Corpus ID: 40247589
Gimap5, a member of the GTPase of the immunity-associated protein family (Gimap), regulates T cell survival. A strong indication…
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Highly Cited
2006
Highly Cited
2006
IAN Family Critically Regulates Survival and Development of T Lymphocytes
T. Nitta
,
Mariam Nasreen
,
+6 authors
Y. Takahama
PLoS biology
2006
Corpus ID: 25195518
The IAN (immune-associated nucleotide-binding protein) family is a family of functionally uncharacterized GTP-binding proteins…
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Review
2004
Review
2004
Rat models of type 1 diabetes: genetics, environment, and autoimmunity.
J. Mordes
,
R. Bortell
,
E. Blankenhorn
,
A. Rossini
,
D. Greiner
ILAR journal
2004
Corpus ID: 24661826
For many years, the vast amount of data gathered from analysis of nonobese diabetic (NOD) and congenic NOD mice has eclipsed…
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Highly Cited
2002
Highly Cited
2002
Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.
A. Macmurray
,
D. Moralejo
,
+17 authors
Å. Lernmark
Genome research
2002
Corpus ID: 2657926
The BB (BioBreeding) rat is one of the best models of spontaneous autoimmune diabetes and is used to study non-MHC loci…
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