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GIMAP5 gene

Known as: IMAP3, GTPase, IMAP family member 5, IAN4L1 
National Institutes of Health

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GIMAP1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
GTPase of the Immune-Associated Nucleotide Protein 5 Regulates the Lysosomal Calcium Compartment in T Lymphocytes
T lymphocytes from Gimap5lyp/lyp rats carrying a recessive mutation in the GTPase of immune-associated protein 5 (Gimap5) gene… 
2016
2016
TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)
GTPase of the immune associated nucleotide binding protein (GIMAP) family of proteins are expressed essentially in cells of the… 
2015
2015
GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes
Long-term survival of T lymphocytes in quiescent state is essential to maintain their cell numbers in secondary lymphoid organs… 
Review
2015
Review
2015
Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut
Inflammatory bowel disease (IBD) including Crohn's disease and ulcerative colitis is often precipitated by an abnormal immune… 
2010
2010
The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein.
A mutation in the rat GIMAP5 gene predisposes for autoimmunity, most famously in the BB rat model of autoimmune type 1 diabetes… 
2010
2010
Forward genetic and cellular studies of immune regulation : the roles of Carma1, Interleukin-10 and Gimap5
2009
2009
Loss of GIMAP5 (GTPase of immunity-associated nucleotide binding protein 5) impairs calcium signaling in rat T lymphocytes.
2009
2009
IAN5 polymorphisms are associated with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a representative autoimmune disease, which is frequently associated with lymphopenia… 
Highly Cited
2008
Highly Cited
2008
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5.
The loss of Gimap5 (GTPase of the immune-associated protein 5) gene function is the underlying cause of lymphopenia and… 
2006
2006
Introgression of F344 Rat Genomic DNA on BB Rat Chromosome 4 Generates Diabetes-Resistant Lymphopenic BB Rats
Failure to express the Gimap5 protein is associated with lymphopenia (lyp) and linked to spontaneous diabetes in the diabetes… 
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