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GI254023X

National Institutes of Health

Papers overview

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2019
2019
The Cxadr–Adam10 complex plays pivotal roles in tight junction integrity and early trophoblast development in mice
Understanding preimplantation embryo development has important implications for assisted reproductive technologies (ARTs) after… 
2017
2017
Neuron-Derived ADAM10 Production Stimulates Peripheral Nerve Injury–Induced Neuropathic Pain by Cleavage of E-Cadherin in Satellite Glial Cells
Background Increasing evidence suggests the potential involvement of metalloproteinase family proteins in the pathogenesis of… 
2016
2016
Activation of the P 2 X 7 receptor induces the rapid shedding of CD 23 from human and murine B cells
Activation of the P2X7 receptor by the extracellular damage-associated molecular pattern, adenosine 5′triphosphate (ATP), induces… 
2015
2015
[Effect of ADAM10 Inhibitor GI254023X on Proliferation and Apoptosis of Acute T-Lymphoblastic Leukemia Jurkat Cells In Vitro and Its Possible Mechanisms].
OBJECTIVE To investigate the effect of ADAM10 inhibitor GI254023X on the proliferation and apoptosis of acute T-lymphoblastic… 
2015
2015
[Effect of ADAM10 Inhibitor GI254023X on Proliferation and Apoptosis of Multiple Myeloma H929 Cells and Its Possible Mechanisms].
OBJECTIVE To investigate the effect of ADAM10 inhibitor GI254023X on the proliferation and apoptosis of multiple myeloma H929… 
2013
2013
Inhibition of Amyloid Precursor Protein Processing Enhances Gemcitabine-mediated Cytotoxicity in Pancreatic Cancer Cells*
Background: Amyloid precursor protein (APP) and ADAM10, main α-secretase involved in generation of secreted APP (sAPPα), are… 
2013
2013
ADAM10 mediates N‐cadherin ectodomain shedding during retinal ganglion cell differentiation in primary cultured retinal cells from the developing chick retina
Here, we examined the role of ADAM10 during retinal cell differentiation in retinal sections and in vitro cultures of developing… 
2009
2009
Involvement of ADAM10 in axonal outgrowth and myelination of the peripheral nerve
The disintegrin and metalloproteinase 10 (ADAM10) is a membrane‐anchored metalloproteinase with both proteolytic and disintegrin… 
2004
2004
Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).
This study shows that the high affinity alpha-chain of the interleukin (IL)-15 receptor exists not only in membrane-anchored but… 
Highly Cited
2003
Highly Cited
2003
Signaling through P2X7 Receptor in Human T Cells Involves p56 lck , MAP Kinases, and Transcription Factors AP-1 and NF-κB*
ATP-gated ion channel P2X receptors are expressed on the surface of most immune cells and can trigger multiple cellular responses… 
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