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GFI1B protein, human

Known as: Gfi-1B protein, human, Gfi-1B proto-oncogene protein, human, GF11B Protein 
Zinc finger protein Gfi-1b (330 aa, ~37 kDa) is encoded by the human GFI1B gene. This protein is involved in both transcriptional regulation and cell… 
National Institutes of Health

Related topics

Related topics

19 relations
Blast Cell ProliferationBone MarrowCYS2-HIS2 Zinc FingersDNA-Binding Proteins

Broader (2)

Proto-Oncogene ProteinsRepressor Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes
Mutations in GFI1B are associated with inherited bleeding disorders called GFI1B-related thrombocytopenias. We show here that… 
2017
2017
Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets
BackgroundChronic fibrosing idiopathic interstitial pneumonia (IIP) is characterized by alveolar epithelial damage, activation of… 
2015
2015
Title : Reciprocal regulation of alternative lineages by Rgs 18 and its transcriptional repressor Gfi 1
  • 2015
  • Corpus ID: 7803208
Appropriate diversification of cellular lineages from multi-potent progenitors is essential for normal development and… 
2014
2014
Regulation of histamine synthesis and tryptase expression through transcription factors, growth factor independent 1 (Gfi1) and Gfi1b, in murine cultured mast cells.
Mast cells are involved in various immunological responses, although it remains unknown how their terminal differentiation is… 
2013
2013
Growth Factor Independence 1b (Gfi1b) Regulates The Commitment, Differentiation and Expansion Of Hematopoietic Stem Cells
The efficacy of bone marrow stem cell transplantation is the therapy of choice for many hematopoietic diseases, in particular… 
Highly Cited
2010
Highly Cited
2010
Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage.
Growth factor independence-1B (Gfi-1B) is a transcriptional repressor essential for erythropoiesis and megakaryopoiesis. Targeted… 
Highly Cited
2005
Highly Cited
2005
Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Immunomodulatory derivative (IMiD) CC-4047, a new analog of thalidomide, directly inhibits growth of B-cell malignancies in vivo… 
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