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GFI1 gene

Known as: ZNF163, GFI1, GROWTH FACTOR-INDEPENDENT 1 
National Institutes of Health

Papers overview

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2012
2012
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
Expression of the transcription repressor Gfi-1 is required for the maintenance of murine hematopoietic stem cells. In human… 
2010
2010
Zinc Finger Protein Gfi1 Controls the Endotoxin-Mediated Toll-Like Receptor Inflammatory Response by Antagonizing NF-κB p65
ABSTRACT Endotoxin (bacterial lipopolysaccharide [LPS]) causes fatal septic shock via the Toll-like receptor 4 (TLR-4) protein… 
2010
2010
Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells.
Ectopic expression of CAAT/enhancer binding protein α (C/EBPα) in p210BCR/ABL-expressing cells induces granulocytic… 
2009
2009
Gfi-1B Promoter Remains Associated with Active Chromatin Marks Throughout Erythroid Differentiation of Human Primary Progenitor Cells
Growth Factor Independent‐1B (Gfi‐1B) is a transcriptional repressor that plays critical roles in the control of erythropoiesis… 
2008
2008
The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response.
2007
2007
Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes.
Gfi1 is a transcriptional repressor essential during myeloid differentiation. Gfi1-/- mice exhibit a block in myeloid… 
2006
2006
Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1
Pulmonary Pseudomonas aeruginosa infections are characterized by the release of proinflammatory mediators, focal induction of… 
2006
2006
Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia.
Granulocyte-colony-stimulating factor (G-CSF) stimulates the activation of multiple signaling pathways, leading to alterations in… 
2005
2005
Gfi-1: another piece in the HSC puzzle.
Highly Cited
1996
Highly Cited
1996
MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene
Infecting mice with a mutant Moloney murine leukemia virus which contains the bacterial suppressor tRNA supF in its LTR allows… 
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