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GFI1 gene

Known as: ZNF163, GFI1, GROWTH FACTOR-INDEPENDENT 1 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1
Type 2 innate lymphoid cells (ILC2 cells) participate in host defense against helminth parasites and in allergic inflammation… 
Highly Cited
2012
Highly Cited
2012
GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.
Recent studies have established that during embryonic development, hematopoietic progenitors and stem cells are generated from… 
Highly Cited
2010
Highly Cited
2010
Gfi1‐Cre knock‐in mouse line: A tool for inner ear hair cell‐specific gene deletion
Gfi1 encodes a zinc‐finger transcription factor essential for the development and maintenance of haematopoiesis and the inner ear… 
Highly Cited
2009
Highly Cited
2009
Gfi1 regulates miR-21 and miR-196b to control myelopoiesis.
The zinc finger protein growth factor independent-1 (Gfi1) is a transcriptional repressor that is critically required for normal… 
Highly Cited
2003
Highly Cited
2003
The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival
Gfi1 was first identified as causing interleukin 2-independent growth in T cells and lymphomagenesis in mice. Much work has shown… 
Highly Cited
2003
Highly Cited
2003
The Transcriptional Repressor Gfi1 Affects Development of Early, Uncommitted c-Kit+ T Cell Progenitors and CD4/CD8 Lineage Decision in the Thymus
In the thymus, several steps of proliferative expansion and selection coordinate the maturation of precursors into antigen… 
Highly Cited
2003
Highly Cited
2003
Gfi‐1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA‐sensitive mechanism
Gfi‐1 and Gfi‐1B can repress transcription and play important roles in hematopoietic cell survival and differentiation. Although… 
Highly Cited
2003
Highly Cited
2003
Targets of the transcriptional repressor oncoprotein Gfi-1
Gfi-1 is a zinc finger transcriptional repressor originally recognized for its role in T cell differentiation and lymphomas… 
Highly Cited
2002
Highly Cited
2002
Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis.
In the search for genes expressed in hematopoietic stem cells, we identified that the expression of Gfi-1B (growth factor… 
Highly Cited
1996
Highly Cited
1996
The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death.
The Gfi-1 protooncogene encodes a nuclear zinc-finger protein that carries a novel repressor domain, SNAG, and functions as a… 
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