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GF 109203X

Known as: GF-109203X, GF109203X 
National Institutes of Health

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1 relation

Broader (1)

bisindolylmaleimide I

Papers overview

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Highly Cited
2005
Highly Cited
2005
Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
Highly Cited
2004
Highly Cited
2004
Protein Kinase Cδ Is Required for p47phox Phosphorylation and Translocation in Activated Human Monocytes1
Our laboratory is interested in understanding the regulation of NADPH oxidase activity in human monocyte/macrophages. Protein… 
Highly Cited
2003
Highly Cited
2003
Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes.
The intestinal brush border (BB) Na+/H+ exchanger isoform 3 (NHE3) is acutely inhibited by elevation in the concentration of free… 
Highly Cited
2003
Highly Cited
2003
Vitamin D receptor is not required for the rapid actions of 1,25‐dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts
The rapid, non‐genomic actions of 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3] have been well described, however, the role of the… 
2002
2002
Temporal activation of p42/44 mitogen-activated protein kinase and c-Jun N-terminal kinase by acetaldehyde in rat hepatocytes and its loss after chronic ethanol exposure.
Several cell-damaging effects of ethanol are due to its major metabolite acetaldehyde but its mechanisms are not known. We have… 
Highly Cited
2001
Highly Cited
2001
Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC…
We reported previously that vascular endothelial growth factor (VEGF) stimulates prostacyclin (PGI(2)) production via activation… 
Highly Cited
1999
Highly Cited
1999
Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells
To elucidate the possibility of utilizing protein kinase C (PKC) isoforms as target genes in neuroblastoma therapy, 5… 
Highly Cited
1998
Highly Cited
1998
Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin‐binding EGF‐like growth factor independently of protein kinase C
The phorbol ester, tetradecanoyl‐phorbol 13‐acetate (TPA), stimulates rapid proteolytic processing of the transmembrane, pro… 
Highly Cited
1998
Highly Cited
1998
Stimulation of p38 Phosphorylation and Activity by Arachidonic Acid in HeLa Cells, HL60 Promyelocytic Leukemic Cells, and Human Neutrophils
Although it is well appreciated that arachidonic acid, a second messenger molecule that is released by ligand-stimulated… 
Highly Cited
1994
Highly Cited
1994
Protein kinase C activity is required for lipid oxidation of low density lipoprotein by activated human monocytes.
Our previous studies have shown that human monocytes can oxidize native low density lipoprotein (LDL) and transform it to a… 
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