GCS-100

Known as: Apoptosis Inducer GCS-100 
A galectin-binding polysaccharide derived from citrus pectin with potential antineoplastic activity. Apoptosis inducer GCS-100 binds to the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2016
0120052016

Papers overview

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2016
2016
Galectin 3 (LGALS3) expression is prognostic for poor survival in acute myeloid leukemia (AML) patients. GCS-100 is a novel… (More)
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2012
2012
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma and an aggressive malignancy. Galectin-3 (gal-3… (More)
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Review
2011
Review
2011
Although modern treatment options for B-chronic lymphocytic leukemia (CLL) produce high response rates, virtually all patients… (More)
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2010
2010
GCS-100 is a galectin-3 antagonist with an acceptable human safety profile that has been demonstrated to have an antimyeloma… (More)
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2010
2010
Human CD8(+) tumor-infiltrating T lymphocytes (TIL), in contrast with CD8(+) blood cells, show impaired IFN-γ secretion on ex… (More)
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2010
2010
GCS-100 is a galectin-3 antagonist with an acceptable human safety profile that has been demonstrated to have an antimyeloma… (More)
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2010
2010
Downlo an CD8 tumor-infiltrating T lymphocytes (TIL), in contrast with CD8 blood cells, show impaired secretion on ex vivo… (More)
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2009
2009
7006 Background: GCS-100 is a polysaccharide antagonist of galectin-3, a protein whose overexpression on certain tumor cells is… (More)
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2006
2006
13023 Background: Galectin-3 is a galactoside-binding protein implicated in inhibition of apoptosis, and promotion of… (More)
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2005
2005
Human multiple myeloma is a presently incurable hematologic malignancy, and novel biologically based therapies are urgently… (More)
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