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Abstract Release of phosphorothioate antisense oligonucleotides (PS-ASOs) from late endosomes (LEs) is a rate-limiting step and a… Expand AIM
HIV-1 Nef downregulates surface MHC-I to protect the infected cells from CTLs-mediated killing. Although MHC-I downregulation… Expand Two distinct domains of GCC185 function in maintaining Golgi structure or in binding to AP-1 to tether retrograde transport… Expand The small GTPase Rab6 regulates vesicle trafficking at the level of Golgi. Recently, the crystal structures of Rab6 in complexes… Expand regulate vesicular transport to and from the Golgi by coordinating the packaging of cargo proteins and their subsequent delivery… Expand !
Force analysis shows the formation of the cover neck bundle (yellow) is at the heart of kinesin's power stroke.
HWANG… Expand Four mammalian golgins are specifically targeted to the trans‐Golgi network (TGN) membranes via their C‐terminal GRIP domains… Expand Mannose 6-phosphate receptors (MPRs) deliver newly synthesized lysosomal enzymes to endosomes and then recycle to the Golgi. MPR… Expand The four mammalian golgins, p230/golgin-245, golgin-97, GCC88 and GCC185 are targeted to trans-Golgi network (TGN) membranes by… Expand The GRIP domain is a targeting sequence found in a family of coiled-coil peripheral Golgi proteins. Previously we demonstrated… Expand