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GC4419

National Institutes of Health

Papers overview

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2020
2020
While radiotherapy is a widely used treatment for many types of human cancer, problems of radio-resistance and side effects… Expand
2020
2020
12071Background: Nephrotoxicity is a major complication of platinum-based chemotherapy and ranges in incidence from 31-68%. The… Expand
2019
2019
PURPOSE Oral mucositis (OM) remains a common, debilitating toxicity of radiation therapy (RT) for head and neck cancer. The goal… Expand
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2019
2019
Severe and recurrent cisplatin-induced acute kidney injury (AKI) as part of standard cancer therapy is a known risk factor for… Expand
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2019
2019
TPS4164Background: Local progression causes up to 30% of deaths from pancreatic cancer (PC) and is also a significant source of… Expand
2018
2018
PURPOSE To assess the safety of the superoxide dismutase mimetic GC4419 in combination with radiation and concurrent cisplatin… Expand
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2018
2018
Lung cancer, together with head and neck cancer, accounts for more than one-fourth of cancer deaths worldwide. New, non-toxic… Expand
Review
2018
Review
2018
The first tenet of medicine, “primum non nocere” or “first, do no harm”, is not always compatible with oncological interventions… Expand
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2017
2017
Elderly cancer patients treated with ionizing radiation (IR) or chemotherapy experience more frequent and greater normal tissue… Expand
2015
2015
To date no models exist to study MnSOD deficiency in human cells. To address this deficiency, we created a SOD2-null human cell… Expand