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GBA wt Allele

Known as: GC, GBA1, GLUC 
Human GBA wild-type allele is located in the vicinity of 1q22 and is approximately 10 kb in length. This allele, which encodes glucosylceramidase… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The discovery of a link between mutations in GBA1, encoding the lysosomal enzyme glucocerebrosidase, and the synucleinopathies… Expand
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Highly Cited
2015
Highly Cited
2015
Autosomal recessively inherited glucocerebrosidase 1 (GBA1) mutations cause the lysosomal storage disorder Gaucher's disease (GD… Expand
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Highly Cited
2014
Highly Cited
2014
Heterozygous mutations in GBA1, the gene encoding lysosomal glucocerebrosidase, are the most frequent known genetic risk factor… Expand
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Highly Cited
2013
Highly Cited
2013
IMPORTANCE While mutations in glucocerebrosidase (GBA1) are associated with an increased risk for Parkinson disease (PD), it is… Expand
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Highly Cited
2013
Highly Cited
2013
Heterozygous loss‐of‐function mutations in the acid beta‐glucocerebrosidase (GBA1) gene, responsible for the recessive lysosomal… Expand
Highly Cited
2011
Highly Cited
2011
Emerging genetic and clinical evidence suggests a link between Gaucher disease and the synucleinopathies Parkinson disease and… Expand
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Highly Cited
2004
Highly Cited
2004
Diffuse large B-cell lymphoma (DLBCL) can be divided into prognostically important subgroups with germinal center B-cell-like… Expand
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Highly Cited
2003
Highly Cited
2003
Treatment with the microsomal enzyme inducer trans-stilbene oxide (TSO) can decrease biliary excretion of acetaminophen… Expand
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Highly Cited
1996
Highly Cited
1996
Abstract Previously, we reported that the spike frequency adaptation and slow afterhyperpolarizations (sAHP) in hippocampal… Expand
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Highly Cited
1995
Highly Cited
1995
Biological markers of internal dose and macromolecular dose from PAHs provide a potential means of assessing environmental… Expand