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G3BP1 gene

Known as: DNA helicase VIII, GTPase-ACTIVATING PROTEIN SH3 DOMAIN-BINDING PROTEIN 1, Ras-GTPase-activating protein SH3-domain-binding protein 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response
RIG-I senses viral RNA in the cytosol and initiates host innate immune response by triggering the production of type 1 interferon… 
Highly Cited
2014
Highly Cited
2014
The Stress Granule Protein G3BP1 Recruits Protein Kinase R To Promote Multiple Innate Immune Antiviral Responses
ABSTRACT Stress granules (SGs) are cytoplasmic storage sites containing translationally silenced mRNPs that can be released to… 
Highly Cited
2013
Highly Cited
2013
Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses
ABSTRACT In response to stress, cells induce ribonucleoprotein aggregates, termed stress granules (SGs). SGs are transient loci… 
Highly Cited
2012
Highly Cited
2012
Large G3BP-induced granules trigger eIF2α phosphorylation
Increasing size of G3BP-induced stress granules is associated with a threshold or switch that must be triggered for eIF2… 
Highly Cited
2011
Highly Cited
2011
A Pseudomonas aeruginosa Toxin that Hijacks the Host Ubiquitin Proteolytic System
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen chronically infecting the lungs of patients with chronic… 
Highly Cited
2007
Highly Cited
2007
The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response.
An essential part of the cellular response to environmental stress is a reversible translational suppression, taking place in… 
Highly Cited
2005
Highly Cited
2005
Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP
ABSTRACT The regulation of mRNA stability plays a major role in the control of gene expression during cell proliferation… 
Highly Cited
2004
Highly Cited
2004
Survival motor neuron protein facilitates assembly of stress granules
Highly Cited
1998
Highly Cited
1998
A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability
ABSTRACT A potential p120 GTPase-activating protein (RasGAP) effector, G3BP (RasGAP Src homology 3 [SH3] binding protein), was… 
Highly Cited
1996
Highly Cited
1996
A Ras-GTPase-activating protein SH3-domain-binding protein
We report the purification of a Ras-GTPase-activating protein (GAP)-binding protein, G3BP, a ubiquitously expressed cytosolic 68… 
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