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G2 Phase Cell Cycle Checkpoints

Known as: G2 Phase Checkpoint, G2 Phase Checkpoints, Checkpoints, G2 Phase 
CELL CYCLE regulatory signaling systems that are triggered by DNA DAMAGE or lack of nutrients during G2 PHASE. When triggered they restrain cells… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The median survival for patients with locally advanced pancreatic cancer treated with gemcitabine and radiation is approximately… Expand
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Highly Cited
2006
Highly Cited
2006
Bioengineering approaches, such as co-cultures of multiple cell types, that aim to mimic the physiological microenvironment may… Expand
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Highly Cited
1999
Highly Cited
1999
The p53 tumor suppressor controls multiple cell cycle checkpoints regulating the mammalian response to DNA damage. To identify… Expand
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Review
1998
Review
1998
The human hepatoma line (Hep G2) has retained the activities of various phase I and phase II enzymes which play a crucial role in… Expand
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Highly Cited
1998
Highly Cited
1998
M‐phase‐promoting factor (MPF), a complex of cdc2 and a B‐type cyclin, is a key regulator of the G2/M cell cycle transition… Expand
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Highly Cited
1997
Highly Cited
1997
Human Cdc25C is a dual-specificity protein phosphatase that controls entry into mitosis by dephosphorylating the protein kinase… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Arrest of the cell cycle in G2 phase following DNA damage helps protect cell viability by allowing time for DNA repair… Expand
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Highly Cited
1992
Highly Cited
1992
We have tested mutants corresponding to 20 DNA repair genes of the fission yeast Schizosaccharomyces pombe for their ability to… Expand
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Highly Cited
1988
Highly Cited
1988
Secretion of plasminogen activator inhibitor 1 (PAI-1) by cultures of human umbilical vein endothelial cells and human… Expand
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Review
1986
Review
1986
Confluent monolayers of the human hepatoblastoma-derived cell line, Hep G2, were incubated in serum-free medium. Conditioned… Expand
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